Results 131 to 140 of about 1,436,726 (254)
Female Reproductive System Neoplasms in Neotropical Primates
ABSTRACT Background There are no previous descriptions of the prevalence of spontaneous female reproductive neoplasms in neotropical primates. Methods A 6‐year study of pathological records from the Anatomy Pathology Sector from the Federal Rural University of Rio de Janeiro (SAP/UFRuralRJ) was conducted.
Asheley H. B. Pereira+7 more
wiley +1 more source
The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells [PDF]
Background Oocytes mature in ovarian follicles surrounded by granulosa cells. During follicle growth, granulosa cells replicate and secrete hormones, particularly steroids close to ovulation.
Glister, Claire+4 more
core +2 more sources
Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation
Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable late recurrent and malignant behavior. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult-type granulosa cell tumor.
Wen-Chung Wang, Yen-Chein Lai
semanticscholar +1 more source
Abstract We report a rare case involving a 22‐year‐old phenotypically female patient who presented to our care with primary amenorrhea and spontaneous breast development. Hormonal analysis indicated hypergonadotropic hypogonadism, and imaging revealed a hypoplastic uterus and calcified ovaries.
Tabatha Petrillo+10 more
wiley +1 more source
The tyrosine kinase inhibitor sunitinib affects ovulation but not ovarian reserve in mouse: A preclinical study [PDF]
The aim of the study was to evaluate ovarian toxicity of tyrosine kinase inhibitor (TKI) sunitinib, since only scarce data are available on gonadal function after this treatment.
Bernard, V. (Valérie)+7 more
core +1 more source
Tumor necrosis factor alpha inhibits ovulation and induces granulosa cell death in rat ovaries
PurposeWe evaluated the role of tumor necrosis factor alpha (TNFα) in rat ovulation and granulosa cell death of ovarian follicles during the periovulatory stage.MethodsImmature rats primed with pregnant mare serum gonadotropin were injected ...
Yuri Yamamoto+9 more
semanticscholar +1 more source
Supplementation with NMN improves oocyte quality in a PCOS mouse model by restoring NAD+ levels, reducing oxidative stress, enhancing mitochondrial function, and preserving spindle integrity. Mechanistically, NMN activates SIRT1 expression via the NAD+ salvage pathway, offering a promising strategy to enhance in vitro maturation and fertility outcomes.
Yong Fan+11 more
wiley +1 more source
Extragonadal LH/hCG action-Not yet time to rewrite textbooks [PDF]
Gonadotropins are indispensable in both sexes in the regulation of gonadal sex steroid production and gametogenesis. In addition to their well-established classical actions, numerous recent publications have indicated the presence and function of ...
Ahtiainen, Petteri+5 more
core +3 more sources
Collision tumor of the colon – colonic adenocarcinoma and ovarian granulosa cell tumor
Background Collision tumors of the colon are rare. We report the first case, to our knowledge in the English literature, of a collision tumor composed of a colonic adenocarcinoma arising in a sigmoid diverticulum coexisting with a recurrent ovarian ...
Kanthan Rani+2 more
doaj +1 more source