Results 131 to 140 of about 10,360,699 (193)

Long Noncoding RNA NONHSAT233728.1 Promotes ROS Accumulation and Granulosa Cell Apoptosis by Regulating the MAPK/ERK1/2 Signaling Pathway

open access: yesThe FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Through isolation and transcriptomic profiling of granulosa cells, we identified the functional significance of lncRNA NONHSAT233728.1 in polycystic ovary syndrome (PCOS) pathogenesis. Knockdown of lncRNA NONHSAT233728.1 in granulosa cells elevated ROS levels, reduced the Bcl2/Bax ratio, downregulated phospho‐ERK1/2, and increased IL‐8 secretion. These
Yao Chen   +5 more
wiley   +1 more source

Association of Sleep, Inflammation and Female Infertility: A Cross‐Sectional Survey and Genetic Approach

open access: yesBrain and Behavior, Volume 15, Issue 6, June 2025.
The association between sleep, inflammation, and female infertility is explored in this study. Preliminary results from a cross‐sectional study involving 307 female infertility participants, drawn from the NHANES database (2013–2020), indicated that women with sleep disorders exhibit abnormal inflammatory states, particularly manifested as altered ...
Xin Xin   +3 more
wiley   +1 more source

Granulosa cell tumor of the ovary

open access: yesTzu Chi Medical Journal, 2016
Wen-Chih Huang   +2 more
openaire   +2 more sources

A Comprehensive Review of Mitochondrial Complex I During Mammalian Oocyte Maturation

open access: yesgenesis, Volume 63, Issue 3, June 2025.
ABSTRACT This review provides a comprehensive overview of Complex I during mammalian oocyte maturation. Complex I (NADH:ubiquinone oxidoreductase) is a crucial member of the electron transport chain and serves two principal functions during oxidative phosphorylation: NADH oxidation and proton pumping.
Nazlican Bozdemir   +3 more
wiley   +1 more source

Coupled Aging of Cyto‐ and Myeloarchitectonic Atlas‐Informed Gray and White Matter Structural Properties

open access: yesHuman Brain Mapping, Volume 46, Issue 8, June 1, 2025.
This longitudinal study investigated the coupling of aging of gray matter and white matter in 102 adults (20–86 years old). Gray matter was parceled into histologically informed von Economo‐Koskinas regions, subtended 3 mm into adjacent white matter.
David A. Hoagey   +3 more
wiley   +1 more source

Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects

open access: yesMedComm, Volume 6, Issue 6, June 2025.
As a polyphenol substance with important potential, resveratrol has important potential in degenerative diseases, cardiovascular diseases, cancer, neurological diseases, etc. However, it is still necessary to pay attention to its bioavailability and potential adverse effects.
Zhuo‐qun Ren   +8 more
wiley   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

open access: yesModern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li   +3 more
wiley   +1 more source

Transcriptional Changes in Cumulus Cells During In Vitro Maturation of Human Oocytes

open access: yesMolecular Reproduction and Development, Volume 92, Issue 6, June 2025.
ABSTRACT This study assessed transcriptional changes in human cumulus cells (CCs) during oocyte maturation In Vitro. CCs were collected from 25 cumulus‐oocyte complexes derived from surplus ovarian medulla tissue of eight women (mean age 29 years, range 19–36) undergoing ovarian tissue cryopreservation without ovarian stimulation.
Jesús Cadenas   +7 more
wiley   +1 more source

Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small‐Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 2, Page 161-167, June 2025.
ABSTRACT Adjuvant chemotherapy is a well‐established treatment for large‐breed dogs with appendicular osteosarcoma; however, it is unclear if it improves outcomes in small‐breed dogs due to limited focused studies. This retrospective study aimed to investigate the oncologic outcomes of dogs weighting less than 15 kg with appendicular osteosarcoma that ...
Stefano Zanardi   +11 more
wiley   +1 more source

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