Results 151 to 160 of about 10,360,699 (193)
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American Journal of Physiology. Endocrinology and Metabolism, 2020
Mitochondrial injury in granulosa cells is associated with the pathogenesis of polycystic ovary syndrome (PCOS). However, the protective effects of melatonin against mitochondrial injury in the granulosa cells of PCOS remain unclear.
Shanling Yi +5 more
semanticscholar +1 more source
Mitochondrial injury in granulosa cells is associated with the pathogenesis of polycystic ovary syndrome (PCOS). However, the protective effects of melatonin against mitochondrial injury in the granulosa cells of PCOS remain unclear.
Shanling Yi +5 more
semanticscholar +1 more source
HMGB1‐induced aberrant autophagy contributes to insulin resistance in granulosa cells in PCOS
The FASEB Journal, 2020Insulin resistance (IR) disrupts ovarian functions in polycystic ovary syndrome (PCOS). The contributing factors remains elusive. High mobility group box 1 (HMGB1), a damage‐associated molecular pattern molecule, has been shown to be related to IR and ...
Chuyue Zhang +4 more
semanticscholar +1 more source
Granulosa cell-oocyte interactions
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004Throughout oogenesis the oocyte and follicle cells establish an intricate system of mutual interactions that ultimately lead to the acquisition of their respective competences. Paracrine factors released by both cell types are believed to stimulate formation of the primordial follicle and support the initial phases of follicle growth. At the same time,
CECCONI, Sandra +4 more
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ULTRASTRUCTURE OF A GRANULOSA CELL TUMOUR
Obstetrical & Gynecological Survey, 1970Abstract. The fine structure of a hormonal active granulosa cell tumour is described. The greater part of the tumour consisted of a cell type resembling the granulosa cell of the normal follicle. It contained many Golgi elements but was poor in smooth and rough endoplasmic reticulum.
Poul Hjortkjaer Pedersen +1 more
openaire +4 more sources
Bioencapsulation of Oocytes and Granulosa Cells
2023A protocol for the encapsulation in sodium alginate of granulosa cells in primary culture and coculture of oocyte-cumulus complexes is reported. Sodium alginate forms strong gels when jellified with barium ions, allowing the self-organization of cells into a 3D structure.
Faustini, Massimo +4 more
openaire +3 more sources
The role of androgen in autophagy of granulosa cells from PCOS
Gynecological Endocrinology, 2019Hyperandrogenism is one of the most common causes for anovulation in women and increases the risk for metabolic disorder in PCOS patients. Autophagy plays an important role in dysfunction of endocrine and anovulation.
Xiaoxue Li +7 more
semanticscholar +1 more source
Clinical correlation of apoptosis in human granulosa cells—A review
Cell Biology International, 2018The quality of oocytes depends on interactions with surrounding granulosa cells. Granulosa cells are essential in normal follicular maturation process since they produce steroidal hormones and growth factors, and they play a crucial role in follicular ...
Camila P. Almeida +8 more
semanticscholar +1 more source
Granulosa Cell Tumor of the Ovary
Journal of Clinical Oncology, 2003Adult granulosa cell tumor (GCT) of the ovary is oftentimes a hormonally active, stromal cell neoplasm that is distinguished by its ability to secrete sex steroids such as estrogen. Patients may present with vaginal bleeding caused by endometrial hyperplasia or uterine cancer as a result of prolonged exposure to tumor-derived estrogen.
Susan Schumer, Stephen A. Cannistra
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2018
Culture of granulosa cells has for long provided a useful tool to understand the molecular processes underlying ovarian follicle development. Among all species investigated, cattle have become an excellent model for in vitro studies on follicular biology, both because of their resemblance with humans in terms of follicular biology and the importance of
Bushra T Mohammed, F. Xavier Donadeu
openaire +3 more sources
Culture of granulosa cells has for long provided a useful tool to understand the molecular processes underlying ovarian follicle development. Among all species investigated, cattle have become an excellent model for in vitro studies on follicular biology, both because of their resemblance with humans in terms of follicular biology and the importance of
Bushra T Mohammed, F. Xavier Donadeu
openaire +3 more sources
Molecular and Cellular Endocrinology, 2004
The ovary is a complex endocrine gland responsible for production of sex steroids and is the source of fertilizable ova for reproduction. It also produces various growth factors, transcription factors and cytokines that assist in the complex signaling pathways of folliculogenesis. The ovary possesses two primary steroidogenic cell types.
Bruce R. Carr +2 more
openaire +3 more sources
The ovary is a complex endocrine gland responsible for production of sex steroids and is the source of fertilizable ova for reproduction. It also produces various growth factors, transcription factors and cytokines that assist in the complex signaling pathways of folliculogenesis. The ovary possesses two primary steroidogenic cell types.
Bruce R. Carr +2 more
openaire +3 more sources