Results 201 to 210 of about 113,926 (280)

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, Mariia Moshkova, Iuliia Pilipenko, David W. Cescon, Eugenia Kumacheva   +7 more
wiley   +1 more source

A complex reciprocal translocation is linked to reduced gamete viability in a loose-bunch grapevine somatic variant. [PDF]

BMC Plant Biol
Alañón-Sánchez N, Ferradás Y, Bezrukov I, Weigel D, Carbonell-Bejerano P, Ibáñez J.   +5 more
europepmc   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Physiological and biochemical responses of twelve autochthonous grapevine varieties to summer stress in the Douro Demarcated Region. [PDF]

Front Plant Sci
Gaspar M, Carvalho M, Baltazar M, Ferreira H, Valente J, Alves F, Castro I, Gonçalves B.   +7 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Decoding Heat-Shock Responses in <i>Vitis vinifera</i> L. by Metabolic, VOC, and Physiological Profiling: Toward the Identification of Volatile and Metabolic Biomarkers. [PDF]

J Agric Food Chem
Pettenuzzo S, Roverso M, Faralli M, Franceschi P, Costantini L, Betta E, Biasioli F, Bogialli S, Grando MS, Cappellin L.   +9 more
europepmc   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats. [PDF]

FEMS Yeast Res
Fay JC, Miller JH, Dashko S, Hyma KE, Liu P, Volk H, Cohen H, Rahman NF, Tang K, Longan ER, Li XC, Butinar L, Piškur J.   +12 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

<i>In Silico</i> Structural Analysis of the Grapevine Serine Protease VviSBT4.19 Involved in Defense against <i>P. viticola</i>. [PDF]

J Agric Food Chem
Rodrigues FEP, Ferreira SGF, Paiva-Silva C, Figueiredo A, Santos RB, Machuqueiro M.   +5 more
europepmc   +1 more source