Results 181 to 190 of about 20,914 (286)

Responding to Stress: Diversity and Resilience of Grapevine in a Changing Climate Under the Perspective of Omics Research. [PDF]

Int J Mol Sci
Konecny T, Asatryan A, Binder H.
europepmc   +1 more source

The International Cocoa Genome Sequencing Consortium (ICGS): a coordinated strategy to sequence and analyse Theobroma cacao genome [Draft] [PDF]

, 2008
Allègre, Mathilde, Argout, Xavier, Boccara, Michel, Brunel, Dominique, Bérard, Aurélie, Clément, Didier, Costet, Pierre, Fouet, Olivier, Gramacho, Karina Peres, Guiltinan, Mark J., Infante, D., Kudrna, Dave, Lanaud, Claire, Legavre, Thierry, Risterucci, Ange-Marie, Ruiz, Manuel, Sabau, Xavier, Sidibé-Bocs, Stéphanie, Ssa, Jetty, Tahi, G.Mathias, Udall, Joshua, Wincker, Patrick, Wing, Rod A., Zang, D.   +23 more
core  

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

Accelerating perennial crop improvement via multi-omics-based predictive breeding. [PDF]

Plant Genome
Robinson H, Robles-Zazueta CA, Voss-Fels KP.   +2 more
europepmc   +1 more source

Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects

Advanced Science, EarlyView.
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su, Jian Qin, Hui Shen, Ling‐Li Zeng, Baojuan Li, Jin Liu, Xuemei Song, Li Liu, Weidan Pu, Tongjian Bai, Huaning Wang, Hong Yin, Kai Wang, Lingjiang Li, Dewen Hu   +14 more
wiley   +1 more source

Grapevine phyllosphere pan-metagenomics reveals pan-microbiome structure, diversity, and functional roles in downy mildew resistance. [PDF]

Microbiome
Jin J, Wang X, Zhang X, Mei J, Zheng W, Guo L, Sun H, Zhang L, Liu C, Ye W, Guo L.   +10 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Harnessing clonal diversity in grapevine: from genomic insights to modern breeding applications. [PDF]

Theor Appl Genet
Callipo P, Schmidt M, Strack T, Robinson H, Vasudevan A, Voss-Fels KP.   +5 more
europepmc   +1 more source

Collaborative program AVRDC/CIRAD : Set up of techniques for: Onion breeding and galrlic dissemination [PDF]

, 2005
Chang, C.H., Cherng, S.J., Engle, L.M., Féréol, Léonidas, Gniffke, P.A., Green, S., Ledesma, D.R.   +6 more
core  

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source