Results 241 to 250 of about 20,914 (286)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

In Vitro Regeneration of Southern Italian Grapevine Cultivars from Embryogenic Calluses and Protoplasts. [PDF]

Plants (Basel)
Ereddia V, Catalano C, Salonia F, Poles L, Bertini E, Zenoni S, Sparacio A, Oliva D, Nicolosi E, Gentile A.   +9 more
europepmc   +1 more source

Chromosome-level reference genome of <i>Vitis piasezkii</i> var. <i>pagnucii</i> provides insights into a new locus of resistance to grapevine powdery mildew. [PDF]

Hortic Res
Zhao L, Hu Y, Ji QY, Gong LX, Lu MJ, Yu XN, Jin ZS, Zhou M, Dai XL, Xiao SY, Jiang Y, Wen YQ.   +11 more
europepmc   +1 more source

Functional Characterization of Grapevine <i>VviMYC4</i> in Regulating Drought Tolerance by Mediating Flavonol Biosynthesis. [PDF]

Plants (Basel)
Tan Y, Wang W, Tian W, Wang B, Zhao Q, Liang J, Zhao W, Wen P.   +7 more
europepmc   +1 more source

Deep learning empowers genomic selection of pest-resistant grapevine. [PDF]

Hortic Res
Gan Y, Liu Z, Zhang F, Xu Q, Wang X, Xue H, Su X, Ma W, Long Q, Ma A, Huang G, Liu W, Xu X, Sun L, Zhang Y, Liu Y, Fang X, Li C, Yang X, Wei P, Fan X, Zhang C, Zhang P, Liu C, Zhou L, Zhang Z, Wang Y, Liu Z, Zhou Y.   +28 more
europepmc   +1 more source

Assessing the efficacy of thermotherapy combined with chemotherapy or cryotherapy for the eradication of grapevine leafroll-associated virus 3. [PDF]

Front Plant Sci
Wante SP, Chooi KM, Pathirana R, Whibley A, Bradley EL, Liau Y, Vanga BR, Hill AM, Lizamore D.   +8 more
europepmc   +1 more source

Optimizing reference gene selection for accurate gene expression analysis in plants. [PDF]

Plant Signal Behav
Xiong Z, Fu C, Huang S, Shi J.
europepmc   +1 more source