Results 51 to 60 of about 20,914 (286)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

RECOMMENDED TABLE GRAPEVINE VARIETIES OF PRIVATE BREEDING [PDF]

open access: yesRussian Vine, 2020
The development of the table grapes market is directly related to the renewal of the assort-ment and technological modernization of pro-duction, taking into account the growing re-quirements of consumers. Equally important is the discrepancy between the tastes of con-sumers of fresh grapes and the quality indica-tors of the grapes supplied by the ...
openaire   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Drawing Links from Transcriptome to Metabolites: The Evolution of Aroma in the Ripening Berry of Moscato Bianco (Vitis vinifera L.)

open access: yesFrontiers in Plant Science, 2017
Monoterpenes confer typical floral notes to “Muscat” grapevine varieties and, to a lesser extent, to other aromatic non-Muscat varieties. Previous studies have led to the identification and functional characterization of some enzymes and genes in this ...
Laura Costantini   +11 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Assessing the identity of the variety "Pedro Giménez" grown in Argentina through the use of microsatellite markers. [PDF]

open access: yes, 2011
'Pedro Giménez' es una variedad criolla blanca cultivada en Argentina, principalmente en las provincias de Mendoza y San Juan, siendo la variedad con la mayor superficie entre las uvas blancas de vinificación.
Agüero, Cecilia B.   +2 more
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Non-destructive quantification of key quality characteristics in individual grapevine berries using near-infrared spectroscopy

open access: yesFrontiers in Plant Science
It is crucial for winegrowers to make informed decisions about the optimum time to harvest the grapes to ensure the production of premium wines. Global warming contributes to decreasing acidity and increasing sugar levels in grapes, resulting in bland ...
Lucie Cornehl   +7 more
doaj   +1 more source

Use of SSR and retrotransposon-based markers to interpret the population structure of native grapevines from Southern Italy [PDF]

open access: yes, 2014
Native grapevines are the quintessential ele- ments of Southern Italy winemaking, and genomic char- acterization plays a role of primary importance for preservation and sustainable use of these unexploited genetic resources.
A Ergul   +67 more
core   +1 more source

Grapevine pangenome facilitates trait genetics and genomic breeding [PDF]

open access: yesNature Genetics
Grapevine breeding is hindered by a limited understanding of the genetic basis of complex agronomic traits. This study constructs a graph-based pangenome reference (Grapepan v.1.0) from 18 newly generated phased telomere-to-telomere assemblies and 11 published assemblies.
Zhongjie Liu   +40 more
openaire   +2 more sources

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