Results 101 to 110 of about 206,716 (316)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The Current Landscape of Scalable Dynamic Graph Processing

IEEE Access
With the rapid growth in data volume, workloads from various domains have undergone drastic changes in recent years. Today, streaming workloads are commonplace.
Gabriel G. Dos Santos, Cesar A. F. de Rose, Kartik Lakhotia   +2 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

GRAph Parallel Actor Language — A Programming Language for Parallel

, 2013
All Rights Reservediii We introduce a domain-specific language, GRAph PArallel Actor Language, that enables parallel graph algorithms to be written in a natural, high-level form.
Graph Algorithms, Michael Delorimier
core  

Graph algorithms for predicting subcellular localization at the pathway level [PDF]

Pac Symp Biocomput, 2023
Magnano CS, Gitter A.
europepmc   +1 more source

Dynamic Algorithms for Graph Coloring [PDF]

, 2018
We design fast dynamic algorithms for proper vertex and edge colorings in a graph undergoing edge insertions and deletions. In the static setting, there are simple linear time algorithms for $(Δ+1)$- vertex coloring and $(2Δ-1)$-edge coloring in a graph with maximum degree $Δ$.
Sayan Bhattacharya, Deeparnab Chakrabarty, Monika Henzinger, Danupon Nanongkai   +3 more
openaire   +4 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Finding the most relevant fragments in networks [PDF]

, 2010
We study a point pattern detection problem on networks, motivated by applications in geographical analysis, such as crime hotspot detection. Given a network N (a connected graph with non-negative edge lengths) together with a set of sites, which lie on ...
Rote, G., Gudmundsson, J., Speckmann, B.; id_orcid, Buchin, K., Silveira, R.I., Speckmann, B., Cabello, S., Löffler, M., Luo, J., Wolle, T.   +9 more
core   +1 more source

Optimizing k-Removal AUC for Urban Infrastructure Networks

IEEE Access
This paper presents a single-city case study (Seaside, Oregon) that ranks cross-layer infrastructure nodes (transport, power, and water) by directly optimizing early service-loss AUC.
Himadri Sen Gupta
doaj   +1 more source