Results 81 to 90 of about 1,814,953 (245)

Containment Graphs, Posets, and Related Classes of Graphs [PDF]

Annals of the New York Academy of Sciences, 1989
In this paper, we introduce the notion of the containment graph of a family of sets and containment classes of graphs and posets. Let $Z$ be a family of nonempty sets. We call a (simple, finite) graph G = (V, E) a $Z$-containment graph provided one can assign to each vertex $v_i \in V $ a set $S_i \in Z$ such that $v_i v_j \in E$ if and only if $S_i ...
Martin Charles Golumbic, Edward R. Scheinerman   +1 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

On the Regular Power Graph on the Conjugacy Classes of Finite Groups [PDF]

Mathematics Interdisciplinary Research, 2018
The (undirected) power graph on the conjugacy classes PC(G) of a group G  is a simple graph in which the vertices are the conjugacy classes of G and two distinct vertices C and C' are adjacent in PC(G) if one is a subset of a power of the other.
Sajjad Mahmood Robati
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

On permutation classes defined by token passing networks, gridding matrices and pictures : three flavours of involvement [PDF]

, 2007
The study of pattern classes is the study of the involvement order on finite permutations. This order can be traced back to the work of Knuth. In recent years the area has attracted the attention of many combinatoralists and there have been many ...
Waton, Stephen D.
core   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Pelabelan Prima pada Kelas Graf Hasil Operasi Perkalian Tensor

Jambura Journal of Mathematics
A graph  with a vertex set   is said to be a prime graph if there exists a bijective mapping , where  denotes the number of vertices in , such that for any two adjacent vertices  and  in  have . Tensor Product graph is a way to combine (compose)
Suci Triwahyuniti, Desi Rahmadani
doaj   +1 more source

A Concise Study of Some Superhypergraph classes [PDF]

Neutrosophic Sets and Systems
In graph theory, the hypergraph extends the traditional graph structure by allowing edges to connect multiple vertices, and this concept is further broadened by the superhypergraph.
Florentin Smarandache, Takaaki Fujita
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source