Results 51 to 60 of about 3,440 (243)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Line game-perfect graphs [PDF]
Discrete Mathematics & Theoretical Computer ScienceThe $[X,Y]$-edge colouring game is played with a set of $k$ colours on a graph $G$ with initially uncoloured edges by two players, Alice (A) and Bob (B). The players move alternately. Player $X\in\{A,B\}$ has the first move. $Y\in\{A,B,-\}$.
Stephan Dominique Andres, Wai Lam Fong
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A rainbow blow-up lemma for almost optimally bounded edge-colourings
Forum of Mathematics, Sigma, 2020 A subgraph of an edge-coloured graph is called rainbow if all its edges have different colours. We prove a rainbow version of the blow-up lemma of Komlós, Sárközy, and Szemerédi that applies to almost optimally bounded colourings.
Stefan Ehard, Stefan Glock, Felix Joos
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
New strong colouring of hypergraphs
Le Matematiche, 2011 We define a new colouring for a hypergraph, in particular for a graph. Such a method is a partition of the vertex-set of a hypergraph, in particular of a graph.
Sandro Rajola, Maria Scafati Tallini
doaj
Optimalisasi Fase Dan Durasi Lampu Lalu Lintas Bundaran Digulis Pontianak
Jurnal DerivatDigulis Roundabout Pontianak is one of the intersections that has a fairly heavy traffic flow that often causes congestion at this intersection. Therefore, it is necessary to optimise the phase and duration of traffic lights by applying fuzzy graph to ...
Harry Evendy Sijabat +2 more
doaj +1 more source
A fuzzy irregular cellular automata-based method for the vertex colouring problem
Connection Science, 2020 Vertex colouring is among the most important problems in graph theory which has been widely applied across different real-world problems. In vertex colouring problem (VCP), the goal is to assign a distinct colour to each vertex of the graph in such a way
Mostafa Kashani +2 more
doaj +1 more source