Results 71 to 80 of about 4,256 (307)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Obstructions to some injective oriented colourings

open access: yesTheory and Applications of Graphs
Each of several possible definitions of local injectivity for a homomorphism of an oriented graph $G$ to an oriented graph $H$ leads to an injective oriented colouring problem.
Russell J Campbell   +2 more
doaj   +1 more source

Finding a Strong Stable Set or a Meyniel Obstruction in any Graph [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
A strong stable set in a graph $G$ is a stable set that contains a vertex of every maximal clique of $G$. A Meyniel obstruction is an odd circuit with at least five vertices and at most one chord.
Kathie Cameron, Jack Edmonds
doaj   +1 more source

Mixed graph colouring as scheduling multi-processor tasks with equal processing times

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2021
A problem of scheduling partially ordered unit-time tasks processed on dedicated machines is formulated as a mixed graph colouring problem, i. e., as an assignment of integers (colours) {1, 2, …, t} to the vertices (tasks) V {ν1, ν2, …, νn}, of the mixed
Yuri N. Sotskov
doaj   +1 more source

Game Colouring Directed Graphs [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2010
In this paper, a colouring game and two versions of marking games (the weak and the strong) on digraphs are studied. We introduce the weak game chromatic number $\chi_{\rm wg}(D)$ and the weak game colouring number ${\rm wgcol}(D)$ of digraphs $D$. It is proved that if $D$ is an oriented planar graph, then $\chi_{\rm wg}(D)$ $\le {\rm wgcol}(D) \le 9$,
Daqing Yang, Xuding Zhu
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Forbidden Structures for Planar Perfect Consecutively Colourable Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2017
A consecutive colouring of a graph is a proper edge colouring with posi- tive integers in which the colours of edges incident with each vertex form an interval of integers.
Borowiecka-Olszewska Marta   +1 more
doaj   +1 more source

Cyclic labellings with constraints at two distances [PDF]

open access: yes, 2004
Motivated by problems in radio channel assignment, we consider the vertex-labelling of graphs with non-negative integers. The objective is to minimise the span of the labelling, subject to constraints imposed at graph distances one and two.
S D Noble   +3 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A note on face coloring entire weightings of plane graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2014
Given a weighting of all elements of a 2-connected plane graph G = (V,E, F), let f(α) denote the sum of the weights of the edges and vertices incident with the face _ and also the weight of _.
Jendrol Stanislav, Šugerek Peter
doaj   +1 more source

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