Results 71 to 80 of about 4,256 (307)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Obstructions to some injective oriented colourings
Each of several possible definitions of local injectivity for a homomorphism of an oriented graph $G$ to an oriented graph $H$ leads to an injective oriented colouring problem.
Russell J Campbell +2 more
doaj +1 more source
Finding a Strong Stable Set or a Meyniel Obstruction in any Graph [PDF]
A strong stable set in a graph $G$ is a stable set that contains a vertex of every maximal clique of $G$. A Meyniel obstruction is an odd circuit with at least five vertices and at most one chord.
Kathie Cameron, Jack Edmonds
doaj +1 more source
Mixed graph colouring as scheduling multi-processor tasks with equal processing times
A problem of scheduling partially ordered unit-time tasks processed on dedicated machines is formulated as a mixed graph colouring problem, i. e., as an assignment of integers (colours) {1, 2, …, t} to the vertices (tasks) V {ν1, ν2, …, νn}, of the mixed
Yuri N. Sotskov
doaj +1 more source
Game Colouring Directed Graphs [PDF]
In this paper, a colouring game and two versions of marking games (the weak and the strong) on digraphs are studied. We introduce the weak game chromatic number $\chi_{\rm wg}(D)$ and the weak game colouring number ${\rm wgcol}(D)$ of digraphs $D$. It is proved that if $D$ is an oriented planar graph, then $\chi_{\rm wg}(D)$ $\le {\rm wgcol}(D) \le 9$,
Daqing Yang, Xuding Zhu
openaire +2 more sources
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Forbidden Structures for Planar Perfect Consecutively Colourable Graphs
A consecutive colouring of a graph is a proper edge colouring with posi- tive integers in which the colours of edges incident with each vertex form an interval of integers.
Borowiecka-Olszewska Marta +1 more
doaj +1 more source
Cyclic labellings with constraints at two distances [PDF]
Motivated by problems in radio channel assignment, we consider the vertex-labelling of graphs with non-negative integers. The objective is to minimise the span of the labelling, subject to constraints imposed at graph distances one and two.
S D Noble +3 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A note on face coloring entire weightings of plane graphs
Given a weighting of all elements of a 2-connected plane graph G = (V,E, F), let f(α) denote the sum of the weights of the edges and vertices incident with the face _ and also the weight of _.
Jendrol Stanislav, Šugerek Peter
doaj +1 more source

