Results 81 to 90 of about 901,024 (319)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Line game-perfect graphs [PDF]
Discrete Mathematics & Theoretical Computer ScienceThe $[X,Y]$-edge colouring game is played with a set of $k$ colours on a graph $G$ with initially uncoloured edges by two players, Alice (A) and Bob (B). The players move alternately. Player $X\in\{A,B\}$ has the first move. $Y\in\{A,B,-\}$.
Stephan Dominique Andres, Wai Lam Fong
doaj +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
A rainbow blow-up lemma for almost optimally bounded edge-colourings
Forum of Mathematics, Sigma, 2020 A subgraph of an edge-coloured graph is called rainbow if all its edges have different colours. We prove a rainbow version of the blow-up lemma of Komlós, Sárközy, and Szemerédi that applies to almost optimally bounded colourings.
Stefan Ehard, Stefan Glock, Felix Joos
doaj +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
New strong colouring of hypergraphs
Le Matematiche, 2011 We define a new colouring for a hypergraph, in particular for a graph. Such a method is a partition of the vertex-set of a hypergraph, in particular of a graph.
Sandro Rajola, Maria Scafati Tallini
doaj
Optimalisasi Fase Dan Durasi Lampu Lalu Lintas Bundaran Digulis Pontianak
Jurnal DerivatDigulis Roundabout Pontianak is one of the intersections that has a fairly heavy traffic flow that often causes congestion at this intersection. Therefore, it is necessary to optimise the phase and duration of traffic lights by applying fuzzy graph to ...
Harry Evendy Sijabat +2 more
doaj +1 more source