Results 221 to 230 of about 810,661 (307)

Engineering of an Ancestral McbA with Enhanced Domain Mobility Extends Biocatalytic Amide Synthesis Scope

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
We show how engineered ancestral amide bond synthetases (ABSs) together with cofactor recycling using a single polyphosphate kinase paves the way for chemoenzymatic synthesis of pharmacophores. The figure illustrates how ancestral ABS has a more flexible C‐terminal domain, which is associated with enhanced catalytic performance and expanded amine scope.
Elisabeth Söderberg   +5 more
wiley   +1 more source

Integrated Flexible Zwitterionic Electrochemical Sensor Platform for Real‐Time Salivary Glucose Quantification

open access: yesAdvanced Sensor Research, EarlyView.
A flexible electrochemical sensor platform can enable continuous, real‐time monitoring of salivary glucose for applications confined to spaces such as the oral cavity. Surface modifications with Prussian blue, chitosan, and zwitterionic polymers enhance sensitivity, selectivity, and antiadherent performance.
Stephanie Klinghammer   +8 more
wiley   +1 more source

Next‐Generation Supercapacitors: Advances in Binder‐Free Electrodes, Scalable Fabrication, and Emerging Applications

open access: yesAdvanced Sustainable Systems, EarlyView.
Innovative fabrication methods are crucial for developing next‐generation supercapacitors. These techniques optimize electrode structures, boosting energy and power density while enabling scalable production. By overcoming current limitations, advanced fabrication unlocks supercapacitors' potential as efficient, reliable energy storage for diverse ...
Nikita A. Wadodkar   +8 more
wiley   +1 more source

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

open access: yesAdvanced Therapeutics, EarlyView.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack   +13 more
wiley   +1 more source

Graph analytics using vertica relational database

open access: green, 2015
Alekh Jindal   +3 more
openalex   +2 more sources

Elderly Liver Grafts are More Susceptible to Ischemia‐Reperfusion After Prolonged Cold Ischemia than Grafts from Young Donors—An Ex Vivo Liver Machine Perfusion Analysis in Sprague Dawley Rats

open access: yesAdvanced Therapeutics, EarlyView.
This study investigates how donor age and cold ischemia time influence liver perfusion parameters and injury markers. Older livers are more susceptible to longer ischemia times displaying more tissue damage, and higher expression of oxidative stress and apoptosis‐related proteins than livers with shorter ischemia times.
Leonard Boerger   +12 more
wiley   +1 more source

Querying Encrypted Graph Databases

open access: gold, 2018
Nahla Aburawi   +2 more
openalex   +1 more source

Home - About - Disclaimer - Privacy