Advanced Science, EarlyView.Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang +10 more
wiley +1 more source
Exploratory Graph Analysis Failed to Reproduce the Hypothesized Functional Zoning Framework in the OECD Survey on Social and Emotional Skills. [PDF]
Psych JWang L, Ning B.
europepmc +1 more source
Advanced Science, EarlyView.An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang +8 more
wiley +1 more source
Case Report: 40Hz multi-target transcranial alternating current stimulation combined with rehabilitation for post-stroke cognitive impairment. [PDF]
Front PsychiatryLai MH +10 more
europepmc +1 more source
Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer
Advanced Science, EarlyView.This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu +7 more
wiley +1 more source
Neural posterior estimation on exponential random graph models: evaluating bias and implementation challenges. [PDF]
Stat ComputFan Y, White SR.
europepmc +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
Advanced Science, EarlyView.WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Seeing through the virtual reality: the effects of learning environment and task difficulty on difficulty perception, learning outcomes and mental models. [PDF]
Front PsycholShan M, Du S, Shangguan C, Li M.
europepmc +1 more source
Advanced Science, EarlyView.Based on the largest printable mesoscopic perovskite solar cells database we established, stacking model achieved precise PCE prediction (R2 = 0.73, MAE = 2.18%). Multiple experiments verified the accuracy of the model, which guided the fabrication of high‐PCE devices with an efficiency of 19.36%.
Hao Meng +9 more
wiley +1 more source