PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su +7 more
wiley +1 more source
Combustion and Pyrolysis EA-IRMS Techniques to Determine the δ<sup>2</sup>H of Diamonds. [PDF]
Fourel F +4 more
europepmc +1 more source
Chiral‐Encoded Pt‐Ir Surfaces as Apparent Spin Filter for Enhanced Oxygen Reduction
The Chiral‐Induced Spin Selectivity (CISS) effect is employed in chiral‐encoded mesoporous Platinum‐Iridium (Pt‐Ir) electrocatalysts to enhance the oxygen reduction reaction (ORR). A break in spin symmetry leads to a substantial antagonistic difference in activity (>200%) when comparing two enantiomorphs of the same electrode.
Zikkawas Pasom +5 more
wiley +1 more source
Gender-related differences in cognitive performance and cognitive stimulation efficacy in subjects with Parkinson's disease and mild cognitive impairment. [PDF]
Iaccino N +8 more
europepmc +1 more source
CMOS‐Integrated Synaptic Photoreceptor Chip Inspired by Insect Visual Processing
CMOS‐integrated Si QDs/ReS2 synaptic photoreceptor array mimics the parallel processing and wavelength‐selective strategy of insect vision. By combining intrinsic ultraviolet‐violet sensitivity with synaptic plasticity, the chip enables frontend sensory redundancy reduction without external filters, offering a scalable pathway toward lowpower ...
Jian Chai +25 more
wiley +1 more source
Computations in living organisms modeled by marked graphs. [PDF]
Myers JM, Madjid H.
europepmc +1 more source
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin +11 more
wiley +1 more source
An Energy Focusing Flexible and Lightweight Acoustic Metamaterial for Enhanced Ultrasound Power Transfer. [PDF]
Kwon HS, Yu Z, Li X, Dede EM, Lee T.
europepmc +1 more source
Shared white matter connectome-based correlates of self-reproach, response failure, spatial planning, and resilience in patients with subthreshold depression: a graph theory approach. [PDF]
Yun JY +4 more
europepmc +1 more source

