Results 61 to 70 of about 426,579 (276)

Planar Induced Subgraphs of Sparse Graphs [PDF]

, 2014
We show that every graph has an induced pseudoforest of at least $n-m/4.5$ vertices, an induced partial 2-tree of at least $n-m/5$ vertices, and an induced planar subgraph of at least $n-m/5.2174$ vertices. These results are constructive, implying linear-
A. Lubotzky, A.V. Kostochka, A.V. Kostochka, C. Cheng, G. Borradaile, K. Edwards, M.M. Halldórsson   +6 more
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Experiments and a User Study for Hierarchical Drawings of Graphs

IEEE Access, 2023
We present a detailed hierarchical graph drawing technique that is based on the Path Based Framework (PBF). Extensive edge bundling is applied to draw all edges of the graph and the height of the drawing is minimized using compaction.
Panagiotis Lionakis, Giorgos Kritikakis, Ioannis G. Tollis   +2 more
doaj   +1 more source

Grid Representations and the Chromatic Number [PDF]

, 2012
A grid drawing of a graph maps vertices to grid points and edges to line segments that avoid grid points representing other vertices. We show that there is a number of grid points that some line segment of an arbitrary grid drawing must intersect.
Balko, Martin
core   +1 more source

Greedy Rectilinear Drawings

, 2018
A drawing of a graph is greedy if for each ordered pair of vertices u and v, there is a path from u to v such that the Euclidean distance to v decreases monotonically at every vertex of the path.
C Batini, C Icking, CH Papadimitriou, CH Papadimitriou, D Eppstein, G Battista Di, J Wang, M Nöllenburg, M Nöllenburg, MT Goodrich, P Angelini, P Angelini, P Leone, R Dhandapani, R Tamassia, S Alamdari, SS Bridgeman, T Leighton, X He, Xin He   +19 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Online Dynamic Graph Drawing [PDF]

IEEE Transactions on Visualization and Computer Graphics, 2008
This paper presents an algorithm for drawing a sequence of graphs online. The algorithm strives to maintain the global structure of the graph and thus the user's mental map, while allowing arbitrary modifications between consecutive layouts. The algorithm works online and uses various execution culling methods in order to reduce the layout time and ...
Yaniv, Frishman, Ayellet, Tal
openaire   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Planar L-Drawings of Directed Graphs

, 2017
We study planar drawings of directed graphs in the L-drawing standard. We provide necessary conditions for the existence of these drawings and show that testing for the existence of a planar L-drawing is an NP-complete problem.
A Garg, EM Kornaropoulos, G Battista Di, G Battista Di, G Battista Di, M Gronemann, M Gronemann, MA Bekos, P Angelini, T Bläsius, U Fößmeier, W Barth, W Didimo   +12 more
core   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source