Results 41 to 50 of about 51,611 (258)

GRIP: Graph Drawing with Intelligent Placement

Journal of Graph Algorithms and Applications, 2002
This paper describes a system for Graph dRawing with Intelligent Placement, GRIP\xspace. The system is designed for drawing large graphs and uses a novel multi-dimensional force-directed method together with fast energy function minimization.
Pawel Gajer, Stephen Kobourov
doaj   +1 more source

Monotone Drawings of Planar Graphs [PDF]

Journal of Graph Theory, 2002
AbstractLet G be a graph drawn in the plane so that its edges are represented by x‐monotone curves, any pair of which cross an even number of times. We show that G can be redrawn in such a way that the x‐coordinates of the vertices remain unchanged and the edges become non‐crossing straight‐line segments. © 2004 Wiley Periodicals, Inc.
Pach, János, Tóth, Géza
openaire   +3 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Fully Dynamic 3-Dimensional Orthogonal Graph Drawing

Journal of Graph Algorithms and Applications, 2001
In a 3-dimensional orthogonal drawing of a graph, vertices are mapped to grid points on a 3-dimensional rectangular integer lattice and edges are routed along integer grid lines. In this paper, we present a technique that produces a 3D orthogonal drawing
M. Closson, S. Gartshore, J. Johansen, S. Wismath   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Track Layouts of Graphs [PDF]

Discrete Mathematics & Theoretical Computer Science, 2004
A \emph(k,t)-track layout of a graph G consists of a (proper) vertex t-colouring of G, a total order of each vertex colour class, and a (non-proper) edge k-colouring such that between each pair of colour classes no two monochromatic edges cross.
Vida Dujmović, Attila Pór, David R. Wood   +2 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Dynamic Spectral Layout with an Application to Small Worlds

Journal of Graph Algorithms and Applications, 2007
Spectral methods are naturally suited for dynamic graph layout because, usually, moderate changes of a graph yield moderate changes of the layout. We discuss some general principles for dynamic graph layout and derive a dynamic spectral layout approach ...
Ulrik Brandes, Daniel Fleischer, Thomas Puppe   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source