Results 81 to 90 of about 649,217 (300)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Faster Graph Embeddings via Coarsening [PDF]
, 2020 Graph embeddings are a ubiquitous tool for machine learning tasks, such as node classification and link prediction, on graph-structured data. However, computing the embeddings for large-scale graphs is prohibitively inefficient even if we are interested ...
Goranci, Gramoz +4 more
core +1 more source
On embedding a cycle in a plane graph [PDF]
Discrete Mathematics, 2006 The problem of drawing a non-simple cycle as a non-intersecting closed curve into a planar graph drawn in the plane with the vertices represented as circles and the edges represented as thin stripes is considered. The problem is shown to have an interpretation in the \textit{clustered planarity}.
Pier Francesco Cortese +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
SocialJGCF: Social Recommendation with Jacobi Polynomial-Based Graph Collaborative Filtering
Applied SciencesWith the flourishing of social media platforms, data in social networks, especially user-generated content, are growing rapidly, which makes it hard for users to select relevant content from the overloaded data.
Heng Lu, Ziwei Chen
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Regular embeddings of complete bipartite maps: classification and enumeration
The regular embeddings of complete bipartite graphs Kn, n in orientable surfaces are classified and enumerated, and their automorphism groups and combinatorial properties are determined.
Jones, Gareth
core +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Journal of Combinatorial Theory, Series B, 1990 Let G be a graph of small maximum degree, which is contained in a chordal graph of small clique number. Is G then contained in a chordal graph of small maximum degree as well? This extremal problem arises from the following: suppose we seek a binary tree T and an injective mapping from V(G) to V(T) (and which sends edges of G to paths in T) so that we ...
openaire +1 more source