Results 91 to 100 of about 649,217 (300)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Restage: Relation Structure-Aware Hierarchical Heterogeneous Graph Embedding

open access: yesTsinghua Science and Technology
Heterogeneous graphs contain multiple types of entities and relations, which are capable of modeling complex interactions. Embedding on heterogeneous graphs has become an essential tool for analyzing and understanding such graphs.
Huanjing Zhao   +4 more
doaj   +1 more source

Parameterized streaming : maximal matching and vertex cover [PDF]

open access: yes, 2014
As graphs continue to grow in size, we seek ways to effectively process such data at scale. The model of streaming graph processing, in which a compact summary is maintained as each edge insertion/deletion is observed, is an attractive one.
Chitnis, Rajesh; id_orcid   +11 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Graph-based Syntactic Word Embeddings

open access: yes, 2020
We propose a simple and efficient framework to learn syntactic embeddings based on information derived from constituency parse trees. Using biased random walk methods, our embeddings not only encode syntactic information about words, but they also ...
Al-Ghezi, Ragheb, Kurimo, Mikko
core   +1 more source

Patient Similarity via Joint Embeddings of Medical Knowledge Graph and Medical Entity Descriptions

open access: yesIEEE Access, 2020
With the prevalence and growing volume of Electronic Health Records (EHRs), there has been increasing interest in mining EHRs for improving clinical decision support.
Zhihuang Lin, Dan Yang, Xiaochun Yin
doaj   +1 more source

Densely embedded graphs

open access: yesJournal of Combinatorial Theory, Series B, 1992
Let G be a graph embedded in a surface S. The face-width of the embedding is the minimum size \(| C\cap G|\) over all noncontractible cycles C in S. The face-width measures how densely a graph is embedded in a surface; equivalently, how well an embedded graph represents a surface.
openaire   +1 more source

Geometrical embeddings of graphs

open access: yesDiscrete Mathematics, 1989
First the paper considers generalized threshold graphs and gives a characterization of such graphs by a list of 11 forbidden induced subgraphs \((G_ 8\) being superfluous since it contains \(G_ 2\) as an induced subgraph). Then the scalar product dimension d(G) of a graph \(G=(V,E)\) is defined to be the minimum number d such that there exists a ...
Jan Reiterman   +2 more
openaire   +2 more sources

Hebbian Graph Embeddings

open access: yes, 2020
Representation learning has recently been successfully used to create vector representations of entities in language learning, recommender systems and in similarity learning.
Shalin Shah
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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