Results 101 to 110 of about 1,795,811 (300)

Network dynamics on graphops

New Journal of Physics, 2020
In this article we report on a novel way to incorporate complex network structure into the analysis of interacting particle systems. More precisely, it is well-known that in well-mixed/homogeneous/all-to-all-coupled systems, one may derive mean-field ...
Christian Kuehn
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Graph-based pattern identification from architecture change logs [PDF]

, 2012
Service-based architectures have become commonplace, creating the need to address their systematic maintenance and evolution. We investigate architecture change representation, primarily focusing on the identification of change patterns that support the ...
Pooyan Jamshidi (5276344), Pooyan Jamshidi, Ahmad, Aakash, Aakash Ahmad, Claus Pahl, Claus Pahl (12588787), Pahl, Claus, Jamshidi, Pooyan, Aakash Ahmad (5022314)   +8 more
core   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

A New Approach for Modeling Vertical Dynamics of Motorcycles Based on Graph Theory

Mathematics
The main objective of this research is to establish a new formulation and mathematical model based on graph theory to create dynamic equations and provide clarity on the fundamental formulation.
Mouad Garziad, Abdelmjid Saka, Hassane Moustabchir, Maria Luminita Scutaru   +3 more
doaj   +1 more source

A Demonstration of the Grrr Graph Rewriting Programming Language [PDF]

, 2000
This paper overviews the graph rewriting programming language, Grrr. The serial graph rewriting strategy is detailed, and key elements of the user interface are described.
Rodgers, Peter, Vidal, Natalia
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Smarandache-Zagreb Index on Three Graph Operators [PDF]

, 2010
Many researchers have studied several operators on a connected graph in which one make an attempt on subdivision of its edges. In this paper, we show how the Zagreb indices, a particular case of Smarandache-Zagreb index of a graph changes with these ...
Ranjini, P.S., Lokesha, V.
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Non-Abelian elastic collisions, associated difference systems of equations and discrete analytic functions

Nuclear Physics B
We extend the equations of motion that describe non-relativistic elastic collision of two particles in one dimension to an arbitrary associative algebra. Relativistic elastic collision equations turn out to be a particular case of these generic equations.
Pavlos Kassotakis, Theodoros Kouloukas, Maciej Nieszporski   +2 more
doaj   +1 more source