Results 81 to 90 of about 1,795,811 (300)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The H-Line Signed Graph of a Signed Graph [PDF]
, 2010 For standard terminology and notion in graph theory we refer the reader to Harary; the non-standard will be given in this paper as and when required.
Reddy, Siva Kota +2 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Forcing (G,D)-number of a Graph [PDF]
, 2011 By a graph G=(V,E), we mean a finite, undirected connected graph without loops and multiple ...
Nagarajan, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Extending the planar theory of anyons to quantum wire networks
SciPost PhysicsThe braiding of the worldlines of particles restricted to move on a network (graph) is governed by the graph braid group, which can be strikingly different from the standard braid group known from two-dimensional physics.
Tomasz Maciazek, Mia Conlon, Gert Vercleyen, J. K. Slingerland
doaj +1 more source
On the stability of solutions of the Oskolkov equations on a graph
, 2010 We consider the problem on the stability of the Oskolkov equations, defined on a finite connected directed graph with the continuity and flow balance conditions at the vertices, with parameters λ0, ν, e{open} ∈ ℝ+.
A. S. Shipilov +3 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2009 For standard terminology and notion in graph theory we refer the reader to Harary [7]; the non-standard will be given in this paper as and when required.
Reddy, P. Siva Kota +3 more
core +1 more source