Results 111 to 120 of about 2,840 (305)

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children

American Journal of Hematology, EarlyView.
ABSTRACT Hydroxyurea (HU) is the most widely prescribed disease‐modifying treatment in sickle cell disease (SCD), though treatment responses vary due to metabolism and adherence. We examined HU blood levels and treatment response in patients with homozygous sickle cell disease (HbSS).
Sigrid van der Veen, Bart J. Biemond, Marjon H. Cnossen, Pablo Bartolucci, Maria P. Boaro, Betzabel Cajiao Garcia, Raffaella Colombatti, M. D'Agnolo, Karin Fijnvandraat, Anna Collado Gimbert, Amira Idrizovic, Petros Kountouris, Mar Mañú‐Pereira, Elisabetta Mezzalira, Mariane de Montalembert, Erfan Nur, A. Pham Hung D' Alexandry D'Orengiani, Tiziana Sanavia, Saskia E. M. Schols, Marissa J. M. Traets, Minke A. E. Rab, Sara I. Reidel, Anita W. Rijneveld, Yosr Zaouali, Nanda M. Verhoeven‐Duif, Judith J. M. Jans, Eduard J. van Beers   +26 more
wiley   +1 more source

Adaptation of the DFD technology in the modeling of business systems in the environment of RDS

Открытое образование (Москва), 2019
The article is devoted to the description of structural methods of processes modeling, represented by visual languages of business processes modeling of socio-economic systems, designed not only for static functional/information modeling of processes ...
G. N. Kalyanov, B. V. Kupriyanov, O. V. Lukinova   +2 more
doaj   +1 more source

Boundary graph grammars with dynamic edge relabeling [PDF]

, 1990
Most NLC-like graph grammars generate node-labeled graphs. As one of the exceptions, eNCE graph grammars generate graphs with edge labels as well. We investigate this type of graph grammar and show that the use of edge labels (together with the NCE ...
Engelfriet, Joost, Welzl, Emo, Leih, George   +2 more
core   +1 more source

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

Animal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala, Mohammadjavad Rezaei‐Varmaziar, Majid Taati, Ali Soleimanzadeh, Abbas Raisi, Farshid Davoodi, Amir Ali Shahbazfar   +6 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Anti‐carbamylated fibrinogen autoantibodies of IgG and IgA isotypes contribute to a better prognostic stratification in very early rheumatoid arthritis: data from the French national ESPOIR cohort

Arthritis &Rheumatology, Accepted Article.
Objective To investigate the prevalence and longitudinal evolution of anti‐carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA), and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti‐cyclic citrullinated peptide antibodies (anti‐CCP) and rheumatoid ...
Pauline Brevet, Olivia Guérin, Léna Le Goaréguer, Élisa Halbourg, Marie‐Laure Golinski, Sophie Candon, Olivier Boyer, Thierry Lequerré, Thierry Schaeverbeke, Valérie Devauchelle‐Pensec, Olivier Vittecoq, Manuel Fréret   +11 more
wiley   +1 more source

Restrictions on NLC graph grammars

Theoretical Computer Science, 1984
An NCL (Node Label Controlled) grammar has productions of the type \(X\to \alpha\) where X is a (nonterminal) label and \(\alpha\) is a graph. The daughter graph can be replaced for a mother node labelled X. Conclusions with the neighborhood of the mother node are established using a connection relation.
Andrzej Ehrenfeucht, Michael G. Main, Grzegorz Rozenberg   +2 more
openaire   +1 more source

Concept Formation Using Graph Grammars [PDF]

, 2002
Recognizing the expressive power of graph representation and the ability of certain graph grammars to generalize, we attempt to use graph grammar learning for concept formation.
Diane J. Cook, Istvan Jonyer, Lawrence B. Holder   +2 more
core  

Using meta-modelling and graph grammars to create modelling environments [PDF]

, 2002
This paper presents the combined use of meta-modelling and graph grammars for the generation of visual modelling tools for simulation formalisms. In meta-modelling, formalisms are described at a meta-level.
Vangheluwe, Hans, Alfonseca Moreno, Manuel, Manuel Alfonseca Moreno, Juan De Lara Jaramillo, Hans Vangheluwe, Lara Jaramillo, Juan de, De Lara Jaramillo, Juan   +6 more
core   +1 more source

Phantom citations: An empirical study of non‐existent and unverifiable references in scholarly literature

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The integrity of scholarly communication depends critically on the accuracy and verifiability of cited references. Citations enable readers to trace prior work, assess evidence, and situate new contributions within the existing literature. However, concerns have emerged regarding the presence of references in published papers that cannot be ...
Chengcheng Han, Sathiamoorthy Manoharan, Xinfeng Ye, Ulrich Speidel   +3 more
wiley   +1 more source