Results 91 to 100 of about 614,117 (293)

Empirical Risk Minimization with Approximations of Probabilistic Grammars [PDF]

, 2010
Probabilistic grammars are generative statistical models that are useful for compositional and sequential structures. We present a framework, reminiscent of structural risk minimization, for empirical risk minimization of the parameters of a fixed ...
Smith, N. A., Cohen, S. B.
core  

The Category of Typed Graph Grammars and its Adjunctions with Categories of Derivations

, 1996
Motivated by the work which has been done for Petri-nets, the paper presents a categorical approach to graph grammars “in the large”. In the large means, that we define categories of graph grammars, graph transition systems, and graph derivation systems ...
Padberg J., MONTANARI, UGO GIOVANNI ERASMO, Loewe M, Ehrig H, CORRADINI, ANDREA   +4 more
core   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Approximate simulation of cortical microtubule models using dynamical graph grammars. [PDF]

Phys Biol, 2023
Medwedeff E, Mjolsness E.
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Deductive parsing with interaction grammars [PDF]

, 2009
We present a parsing algorithm for Interaction Grammars using the deductive parsing framework. This approach brings new perspectives to this problem, departing from previous methods which rely on constraint-solving ...
Le Roux, Joseph
core   +4 more sources

Multiple context-free path querying by matrix multiplication

Научно-технический вестник информационных технологий, механики и оптики
Many graph analysis problems can be formulated as formal language-constrained path querying problems where the formal languages are used as constraints for navigational path queries.
I. V. Epelbaum, R. Sh. Azimov, S. V. Grigorev   +2 more
doaj   +1 more source

Sequence Tagging for Fast Dependency Parsing

Proceedings, 2019
Dependency parsing has been built upon the idea of using parsing methods based on shift-reduce or graph-based algorithms in order to identify binary dependency relations between the words in a sentence.
Michalina Strzyz, David Vilares, Carlos Gómez-Rodríguez   +2 more
doaj   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source