Results 201 to 210 of about 614,117 (293)

Engineering Flexible Nanofibrous Hydroxyapatite Scaffolds With Tunable Degradation and Mechanical Properties for Bone Regeneration

open access: yesSmall, EarlyView.
Conventional hydroxyapatite ceramics are brittle and poorly resorbable, limiting their use in bone repair. To overcome these limitations, flexible scaffolds are fabricated using ceramic nanofibers as structural building blocks. Adjusting nanofiber characteristics allows modulating the mechanical properties and degradation, providing a versatile ...
Raúl Agut López   +4 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Decomposing dynamical subprocesses for compositional generalization. [PDF]

open access: yesProc Natl Acad Sci U S A
Luettgau L   +6 more
europepmc   +1 more source

Influence of Surface Roughness and Temperature on Niobium Cathodic Cage Duplex Treatment Applied to VP20TS Steel

open access: yessteel research international, EarlyView.
Niobium cathodic cage duplex treatment is applied to VP20TS steel to evaluate the influence of surface roughness and temperature on coating performance. Results show that higher temperatures promote thicker nitride layers and increased microhardness, while finer surface preparation enhances adhesion and wear resistance, revealing optimal conditions for
Alan Bruno Costa Cardoso   +6 more
wiley   +1 more source

TRM‐to‐concrete interface bond without anchors: Combined experimental, analytical, and numerical modeling approach

open access: yesStructural Concrete, EarlyView.
Abstract Textile reinforced mortar (TRM) systems have emerged as an effective alternative to conventional FRP strengthening solutions due to their compatibility with concrete substrates and favorable performance under adverse environmental conditions.
Ömer Mercimek   +4 more
wiley   +1 more source

A method for determining the performance of formulas for calculating the crack width and spacing in reinforced concrete elements

open access: yesStructural Concrete, EarlyView.
Abstract Numerous studies have been conducted to determine the performance of formulas for calculating crack width and spacing in reinforced concrete structures. Generally, these studies pay limited attention to the application areas of those formulas and how to compare different representations of the crack width and spacing.
Anton van der Esch   +2 more
wiley   +1 more source

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