Results 131 to 140 of about 2,535,598 (350)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

On Total H-Irregularity Strength of the Disjoint Union of Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2020
A simple graph G admits an H-covering if every edge in E(G) belongs to at least to one subgraph of G isomorphic to a given graph H. For the subgraph H ⊆ G under a total k-labeling we define the associated H-weight as the sum of labels of all vertices and
Ashraf Faraha   +5 more
doaj   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Multi-Label Continual Learning using Augmented Graph Convolutional Network [PDF]

open access: green, 2022
Kaile Du   +7 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Trees whose even-degree vertices induce a path are antimagic

open access: yes, 2019
An antimagic labeling a connected graph $G$ is a bijection from the set of edges $E(G)$ to $\{1,2,\dots,|E(G)|\}$ such that all vertex sums are pairwise distinct, where the vertex sum at vertex $v$ is the sum of the labels assigned to edges incident to ...
Lozano, Antoni   +3 more
core  

Prime Labelings of Snake Graphs

open access: yesThe PUMP Journal of Undergraduate Research, 2019
A prime labeling of a graph G with n vertices is a labeling of the vertices with distinct integers from the set {1, 2 ,..., n} such that the labels of any two adjacent vertices are relatively prime. In this paper, we introduce a snake graph, the fused union of identical cycles, and define a consecutive snake prime labeling for this new family of graphs.
Abigail Bigham   +4 more
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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