Results 81 to 90 of about 1,639,507 (316)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Topological Properties of Neuromorphic Nanowire Networks

Frontiers in Neuroscience, 2020
Graph theory has been extensively applied to the topological mapping of complex networks, ranging from social networks to biological systems. Graph theory has increasingly been applied to neuroscience as a method to explore the fundamental structural and
Alon Loeffler, Ruomin Zhu, Joel Hochstetter, Mike Li, Kaiwei Fu, Adrian Diaz-Alvarez, Tomonobu Nakayama, James M. Shine, Zdenka Kuncic   +8 more
doaj   +1 more source

Graph Kernel Neural Networks

IEEE Transactions on Neural Networks and Learning Systems
The convolution operator at the core of many modern neural architectures can effectively be seen as performing a dot product between an input matrix and a filter. While this is readily applicable to data such as images, which can be represented as regular grids in the Euclidean space, extending the convolution operator to work on graphs proves more ...
Cosmo, Luca, Minello, Giorgia, Bicciato, Alessandro, Bronstein, Michael M., Rodolà, Emanuele, Rossi, Luca, Torsello, Andrea   +6 more
openaire   +4 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Graph Convolutional Network for 3D Object Pose Estimation in a Point Cloud

Sensors, 2022
Graph Neural Networks (GNNs) are neural networks that learn the representation of nodes and associated edges that connect it to every other node while maintaining graph representation.
Tae-Won Jung, Chi-Seo Jeong, In-Seon Kim, Min-Su Yu, Soon-Chul Kwon, Kye-Dong Jung   +5 more
doaj   +1 more source

Stochastic graph recurrent neural network

Neurocomputing, 2022
Representation learning over graph structure data has been widely studied due to its wide application prospects. However, previous methods mainly focus on static graphs while many real-world graphs evolve over time. Modeling such evolution is important for predicting properties of unseen networks.
Yan, Tijin, Zhang, Hongwei, Li, Zirui, Xia, Yuanqing   +3 more
openaire   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Identifying Influential Nodes in Complex Networks Based on Information Entropy and Relationship Strength

Entropy, 2023
Identifying influential nodes is a key research topic in complex networks, and there have been many studies based on complex networks to explore the influence of nodes.
Ying Xi, Xiaohui Cui
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

MGATs: Motif-Based Graph Attention Networks

Mathematics
In recent years, graph convolutional neural networks (GCNs) have become a popular research topic due to their outstanding performance in various complex network data mining tasks.
Jinfang Sheng, Yufeng Zhang, Bin Wang, Yaoxing Chang   +3 more
doaj   +1 more source