Results 71 to 80 of about 197,409 (310)
A modified multilevel k-way partitioning algorithm for trip-based road networks [PDF]
MATEC Web of Conferences, 2019 In today’s world, the traffic volume on urban road networks is multiplying rapidly due to the heavy usage of vehicles and mobility on demand services. Migration of people towards urban areas result in increasing size and complexity of urban road networks.
Withanage C +5 more
doaj +1 more source
Genetic algorithms for graph partitioning and incremental graph partitioning
Proceedings of Supercomputing '94, 1994 Partitioning graphs into equally large groups of nodes, minimizing the number of edges between different groups, is an extremely important problem in parallel computing. This paper presents genetic algorithms for suboptimal graph partitioning, with new crossover operators (KNUX, DKNUX) that lead to orders of magnitude improvement over traditional ...
Maini, Harpal +3 more
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
10 Problems for Partitions of Triangle-free Graphs [PDF]
, 2022 József Balogh +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Improving quality of graph partitioning using multilevel optimization
Труды Института системного программирования РАН, 2018 Graph partitioning is required for solving tasks on graphs that need to be split across disks or computers. This problem is well studied, but most results are not suitable for processing graphs with billons of nodes on commodity clusters, since they ...
R. Pastukhov +3 more
doaj +1 more source
Graph Partition Based on Dimensionless Similarity and Its Application to Fault Diagnosis [PDF]
, 2021 Bo Zheng +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Research on Massive Knowledge Storage for Network Monitoring and Early Warning [PDF]
Jisuanji gongcheng, 2018 Efficient management of massive knowledge is the prerequisite for the effectiveness of network monitoring and early warning.Aiming at this problem,a large-scale Resource Description Framework(RDF) data storage approach is proposed based on graph database.
RAO Zhihong,LIU Jie,CHEN Jianfeng
doaj +1 more source