Results 71 to 80 of about 193,029 (263)

Genetic algorithms for graph partitioning and incremental graph partitioning

Proceedings of Supercomputing '94, 1994
Partitioning graphs into equally large groups of nodes, minimizing the number of edges between different groups, is an extremely important problem in parallel computing. This paper presents genetic algorithms for suboptimal graph partitioning, with new crossover operators (KNUX, DKNUX) that lead to orders of magnitude improvement over traditional ...
Maini, Harpal, Mehrotra, Kishan, Mohan, Chilukuri K., Ranka, Sanjay   +3 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A modified multilevel k-way partitioning algorithm for trip-based road networks [PDF]

MATEC Web of Conferences, 2019
In today’s world, the traffic volume on urban road networks is multiplying rapidly due to the heavy usage of vehicles and mobility on demand services. Migration of people towards urban areas result in increasing size and complexity of urban road networks.
Withanage C, Lakmal D, Hansini M, Kankanamge K, Witharanage Y, Thayasivam U   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Improving quality of graph partitioning using multilevel optimization

Труды Института системного программирования РАН, 2018
Graph partitioning is required for solving tasks on graphs that need to be split across disks or computers. This problem is well studied, but most results are not suitable for processing graphs with billons of nodes on commodity clusters, since they ...
R. Pastukhov, A. Korshunov, D. Turdakov, S. Kuznetsov   +3 more
doaj   +1 more source

Sigma Partitioning: Complexity and Random Graphs [PDF]

Discrete Mathematics & Theoretical Computer Science, 2018
A $\textit{sigma partitioning}$ of a graph $G$ is a partition of the vertices into sets $P_1, \ldots, P_k$ such that for every two adjacent vertices $u$ and $v$ there is an index $i$ such that $u$ and $v$ have different numbers of neighbors in $P_i$. The
Ali Dehghan, Mohammad-Reza Sadeghi, Arash Ahadi   +2 more
doaj   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Beyond pairwise clustering [PDF]

, 2005
We consider the problem of clustering in domains where the affinity relations are not dyadic (pairwise), but rather triadic, tetradic or higher. The problem is an instance of the hypergraph partitioning problem.
Agarwal, Sameer, Belongie, Serge, Kriegman, David, Lim, Jongwoo, Perona, Pietro, Zelnik-Manor, Lihi   +5 more
core   +2 more sources