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Graph Powering and Spectral Robustness [PDF]
Spectral algorithms, such as principal component analysis and spectral clustering, typically require careful data transformations to be effective: upon observing a matrix $A$, one may look at the spectrum of $ (A)$ for a properly chosen $ $. The issue is that the spectrum of $A$ might be contaminated by non-informational top eigenvalues, e.g., due to
Emmanuel Abbe+3 more
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
Forbidden subgraphs of TI-power graphs of finite groups
Given a finite group GG with identity ee, the TI-power graph (trivial intersection power graph) defined on GG, denoted by Γ(G)\Gamma \left(G), is an undirected graph with vertex set GG where distinct vertices aa and bb are adjacent if ⟨a⟩∩⟨b⟩={e}\langle ...
Li Huani, Chen Jin, Lin Shixun
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Stationary Graph Processes and Spectral Estimation
Stationarity is a cornerstone property that facilitates the analysis and processing of random signals in the time domain. Although time-varying signals are abundant in nature, in many practical scenarios the information of interest resides in more ...
Leus, Geert+3 more
core +1 more source
The power of small coalitions in graphs
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bermond, Jean-Claude+3 more
openaire +2 more sources
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Metric and strong metric dimension in TI-power graphs of finite groups
Given a finite group $ G $ with the identity $ e $, the TI-power graph (trivial intersection power graph) of $ G $ is an undirected graph with vertex set $ G $, in which two distinct vertices $ x $ and $ y $ are adjacent if $ \langle x\rangle\cap \langle
Chunqiang Cui, Jin Chen, Shixun Lin
doaj +1 more source
In complex power systems, when power equipment fails, multiple concurrent failures usually occur instead of a single failure. Concurrent failures are so common and hidden in complex systems that diagnosis requires not only analysis of failure ...
Liqing Liu+8 more
doaj +1 more source