RLFDDA: a meta-path based graph representation learning model for drug-disease association prediction. [PDF]
Zhang ML +5 more
europepmc +1 more source
Fiber energy harvesters offer unprecedented flexibility and a unique capacity for integration into commercial textiles, overcoming the limitations of bulky and rigid conventional devices. This review summarizes recent advances in fiber‐based energy harvesting and provides strategic outlooks to accelerate technological progress in the field. ABSTRACT As
Hanhwi Jang +8 more
wiley +1 more source
Enhancing drug-target interaction prediction with graph representation learning and knowledge-based regularization. [PDF]
Yao Q, Chen Z, Cao Y, Hu H.
europepmc +1 more source
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
A Multisource Transformer-Guided Graph Representation Learning Framework for circRNA-Disease Association Prediction. [PDF]
Liang SZ, Wang L, You ZH, Yu CQ.
europepmc +1 more source
Self-supervised graph representation learning integrates multiple molecular networks and decodes gene-disease relationships. [PDF]
Wang Y, Sun Z, He Q, Li J, Ni M, Yang M.
europepmc +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
SuperEdgeGO: Edge-supervised graph representation learning for enhanced protein function prediction. [PDF]
Zhang S +8 more
europepmc +1 more source
Detection of autism spectrum disorder using graph representation learning algorithms and deep neural network, based on fMRI signals. [PDF]
Yousefian A, Shayegh F, Maleki Z.
europepmc +1 more source
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source

