Results 81 to 90 of about 8,038,825 (297)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Restage: Relation Structure-Aware Hierarchical Heterogeneous Graph Embedding

open access: yesTsinghua Science and Technology
Heterogeneous graphs contain multiple types of entities and relations, which are capable of modeling complex interactions. Embedding on heterogeneous graphs has become an essential tool for analyzing and understanding such graphs.
Huanjing Zhao   +4 more
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Representation and generation of plans using graph spectra [PDF]

open access: yes, 2007
Numerical comparison of spaces with one another is often achieved with set scalar measures such as global and local integration, connectivity, etc., which capture a particular quality of the space but therefore lose much of the detail of its overall ...
Hanna, S.
core  

Effective Temporal Graph Learning via Personalized PageRank

open access: yesEntropy
Graph representation learning aims to map nodes or edges within a graph using low-dimensional vectors, while preserving as much topological information as possible.
Ziyu Liao, Tao Liu, Yue He, Longlong Lin
doaj   +1 more source

Representation Learning on Graphs: A Reinforcement Learning Application

open access: yesCoRR, 2019
In this work, we study value function approximation in reinforcement learning (RL) problems with high dimensional state or action spaces via a generalized version of representation policy iteration (RPI). We consider the limitations of proto-value functions (PVFs) at accurately approximating the value function in low dimensions and we highlight the ...
Sephora Madjiheurem, Laura Toni
openaire   +4 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Graph representation learning for single cell biology.

open access: yes, 2021
Single cell RNA sequencing measures gene expression at an unprecedented resolution and scale and allows the analysis of cellular phenotypes which was not possible before.
Hetzel, L.   +3 more
core   +1 more source

A Dual Fusion Pipeline to Discover Tactical Knowledge Guided by Implicit Graph Representation Learning

open access: yesMathematics
Discovering tactical knowledge aims to extract tactical data derived from battlefield signal data, which is vital in information warfare. The learning and reasoning from battlefield signal information can help commanders make effective decisions. However,
Xiaodong Wang   +5 more
doaj   +1 more source

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