Results 111 to 120 of about 622,624 (287)
Graph reconstruction from the observation of diffused signals
, 2015 Signal processing on graphs has received a lot of attention in the recent years. A lot of techniques have arised, inspired by classical signal processing ones, to allow studying signals on any kind of graph.
Gripon, Vincent +4 more
core +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Discover ComputingSensor networks let a farmer keep their eye on multiple locations in an agricultural field simultaneously but can be expensive to install, maintain and analyse.
Jurgen van den Hoogen +2 more
doaj +1 more source
Apply Graph Signal Processing on NILM: An Unsupervised Approach Featuring Power Sequences. [PDF]
Sensors (Basel), 2023 Zhao B, Li X, Luan W, Liu B.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
State Estimation in Partially Observable Power Systems via Graph Signal Processing Tools. [PDF]
Sensors (Basel), 2023 Dabush L, Kroizer A, Routtenberg T.
europepmc +1 more source
Frames for Signal Processing on Cayley Graphs
Journal of Fourier Analysis and ApplicationsThe spectral decomposition of graph adjacency matrices is an essential ingredient in the design of graph signal processing (GSP) techniques. When the adjacency matrix has multi-dimensional eigenspaces, it is desirable to base GSP constructions on a particular eigenbasis that better reflects the graph's symmetries.
Kathryn Beck +3 more
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source