Results 91 to 100 of about 169,163 (265)

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

A Note on the Permanental Roots of Bipartite Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2014
It is well-known that any graph has all real eigenvalues and a graph is bipartite if and only if its spectrum is symmetric with respect to the origin.
Zhang Heping, Liu Shunyi, Li Wei
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Distance-regularity and the spectrum of graphs [PDF]

open access: yesLinear Algebra and its Applications, 1996
This paper considers the question whether a graph with the spectrum of a distance regular graph is distance regular. It has been known that the answer is affirmative if the distance regular graph has diameter not greater than 2, and that the answer is negative if the diameter is greater than 3.
openaire   +4 more sources

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Spectral analysis of the wreath product of a complete graph with a cocktail party graph

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2018
Graph products and the corresponding spectra are often studied in the literature. A special attention has been given to the wreath product of two graphs, which is derived from the homonymous product of groups.
Francesco Belardo   +2 more
doaj   +1 more source

On energy, Laplacian energy and $p$-fold graphs

open access: yesElectronic Journal of Graph Theory and Applications, 2015
For a graph $G$ having adjacency spectrum ($A$-spectrum) $\lambda_n\leq\lambda_{n-1}\leq\cdots\leq\lambda_1$ and Laplacian spectrum ($L$-spectrum) $0=\mu_n\leq\mu_{n-1}\leq\cdots\leq\mu_1$, the energy is defined as $ E(G)=\sum_{i=1}^{n}|\lambda_i|$ and ...
Hilal A Ganie   +2 more
doaj   +1 more source

Distance spectrum of graph compositions

open access: yesArs Mathematica Contemporanea, 2009
The D -eigenvalues μ 1 , μ 2 , ..., μ p of a graph G are the eigenvalues of its distance matrix D and form the distance spectrum or the D -spectrum.  In this paper we obtain the D -spectrum of the cartesian product if two distance regular graphs.
openaire   +2 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

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