Results 51 to 60 of about 179,652 (285)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
On the spectral determinations of the connected multicone graphs
AKCE International Journal of Graphs and Combinatorics, 2020 In this study we investigate the spectra of the family of connected multicone graphs. A multicone graph is defined to be the join of a clique and a regular graph. Let , and be natural numbers, and let denote a complete graph on vertices.
Ali Zeydi Abdian +6 more
doaj +1 more source
On distance Laplacian spectrum of zero divisor graphs of the ring $\mathbb{Z}_{n}$
Karpatsʹkì Matematičnì Publìkacìï, 2021 For a finite commutative ring $\mathbb{Z}_{n}$ with identity $1\neq 0$, the zero divisor graph $\Gamma(\mathbb{Z}_{n})$ is a simple connected graph having vertex set as the set of non-zero zero divisors, where two vertices $x$ and $y$ are adjacent if and
S. Pirzada, B.A. Rather, T.A. Chishti
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The spectral characterization of the connected multicone graphs
AKCE International Journal of Graphs and Combinatorics, 2020 A multicone graph is defined to be the join of a clique and a regular graph. Let , and be natural numbers, and let and denote a complete graph and a complete bipartite graph, respectively.
Ali Zeydi Abdian +2 more
doaj +1 more source
Graph isomorphism and multivariate graph spectrum
Advances in Applied MathematicsWe provide a criterion to distinguish two graphs which are indistinguishable by $2$-dimensional Weisfeiler-Lehman algorithm for almost all graphs. Haemers conjectured that almost all graphs are identified by their spectrum. Our approach suggests that almost all graphs are identified by their generalized block Laplacian spectrum.
Wei Wang 0195, Da Zhao
openaire +2 more sources
Which graphs are determined by their spectrum? [PDF]
Linear Algebra and its Applications, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
van Dam, E.R., Haemers, W.H.
openaire +5 more sources
On the Seidel spectrum of threshold graphs
Indian Journal of Pure and Applied Mathematics, 2023 17 Pages, 1 ...
Santanu Mandal, Ranjit Mehatari
openaire +3 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source