Results 51 to 60 of about 1,217,420 (262)
Comparative Study of Planar Octahedron Molecular Structure via Eccentric Invariants
A branch of graph theory that makes use of a molecular graph is called chemical graph theory. Chemical graph theory is used to depict a chemical molecule. A graph is connected if there is an edge between every pair of vertices.
Zheng-Qing Chu+5 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Knowledge graph analysis of particles in Japanese [PDF]
The theory of knowledge graphs is a structuralistic theory of language. Its ontology consists of eight types of binary relationships and four types of so-called frames. The relationships connect so-called tokens, that represent semantic units.
Hoede, C.
core +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
The Role of Graph Theory in System of Systems Engineering
The world of system of systems engineering (SoSE), and consequently systems engineering, is currently being reformalized so as to provide greater functionality, integration, and extensibility into designed systems of systems (SoS).
Willie K. Harrison
doaj +1 more source
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
This book contains the successful invited submissions [1–10] to a special issue of Symmetry on the subject area of ‘graph theory’ [...]
openaire +2 more sources
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
In this paper we analyze solutions of the problems of the graph theory with computer mathematics systems MAPLE and MATHEMATICA with purpose to reveal the opportunity of the syntax of the main commands, theirs similarities and differences.
Sigita Turskienė+1 more
doaj +1 more source