Results 71 to 80 of about 1,282,116 (277)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Ramsey theory of Henson graphs

open access: yesJournal of Mathematical Logic, 2022
Analogues of Ramsey’s Theorem for infinite structures such as the rationals or the Rado graph have been known for some time. In this context, one looks for optimal bounds, called degrees, for the number of colors in an isomorphic substructure rather than one color, as that is often impossible.
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Role of Graph Theory in System of Systems Engineering

open access: yesIEEE Access, 2016
The world of system of systems engineering (SoSE), and consequently systems engineering, is currently being reformalized so as to provide greater functionality, integration, and extensibility into designed systems of systems (SoS).
Willie K. Harrison
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Automatic theory formation in graph theory

open access: yesJournal of the Brazilian Computer Society, 1999
This paper presents SCOT, a system for automatic theory construction in the domain of Graph Theory. Following on the footsteps of the programs ARE [9], HR [1] and Cyrano [6], concept discovery is modeled as search in a concept space. We propose a classification for discovery heuristics, which takes into account the main processes related to theory ...
Pistori, Hemerson, Wainer, Jacques
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Opportunities analysis the solution of the problems of the graph theory with computer mathematics systems

open access: yesLietuvos Matematikos Rinkinys, 2010
In this paper we analyze solutions of the problems of the graph theory with computer mathematics systems MAPLE and MATHEMATICA with purpose to reveal the opportunity of the syntax of the main commands, theirs similarities and differences.
Sigita Turskienė   +1 more
doaj   +1 more source

On the Edge-Connectivity of an Uncertain Random Graph

open access: yesIEEE Access, 2020
Connectivity is one of the most important concepts in graph theory. When graph theory is applied to complex systems with indeterminate factors, uncertainty and randomness are two basic types of indeterminacy.
Hao Li, Hui Zhang
doaj   +1 more source

Home - About - Disclaimer - Privacy