Results 81 to 90 of about 143,018 (267)
Modular irregularity strength of vertex amalgamation and comb product path with cycle related graphs
Consider a graph G = (V(G), E(G)), where V(G) is a nonempty set of vertices and E(G) is a set of edges. Let Zn be the group of integers modulo n, and let k be a positive integer. A modular irregular labeling of a graph G of order n is a k-edge labeling ϕ
Kiki A. Sugeng +4 more
doaj +1 more source
In this paper, we propose a new type of graph, denoted as "embedded-graph", and its theory, which employs a distributed representation to describe the relations on the graph edges. Embedded-graphs can express linguistic and complicated relations, which cannot be expressed by the existing edge-graphs or weighted-graphs.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Automatic theory formation in graph theory
This paper presents SCOT, a system for automatic theory construction in the domain of Graph Theory. Following on the footsteps of the programs ARE [9], HR [1] and Cyrano [6], concept discovery is modeled as search in a concept space. We propose a classification for discovery heuristics, which takes into account the main processes related to theory ...
Pistori, Hemerson, Wainer, Jacques
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Construction of industry knowledge graph based on graph theory
China has the largest industrial scale and the most abundant industry type among the world.However, due to the influence of many factors, it is necessary to discover the blocking and breakpoints of the industrial chain, identify the stuck points, find ...
Zhenjun LI +6 more
doaj
Note: Professor Pach's number: [172]; 2nd edition Reference DCG-CHAPTER-2008-027 Record created on 2008-11-18, modified on 2017-05 ...
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Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

