Results 81 to 90 of about 7,041,985 (308)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

On the conjunctive capacity of graphs [PDF]

open access: yes, 2013
The investigation of the asymptotic behaviour of various graph parameters in powers of a fixed graph G=(V,E) is motivated by problems in information theory and extremal ...
Chlebikova, Janka   +5 more
core   +1 more source

Zagreb-Based Indices of Line Graph of Prime Coprime Graph for Integers Modulo Group

open access: yesScience and Technology Indonesia
In this paper, we investigate the line graph of the prime coprime graph associated with the integers modulo group. Explicit general formulas are derived for the first Zagreb index, the second Zagreb index, and the hyper-Zagreb index of the considered ...
Abdurahim   +2 more
doaj   +1 more source

Environmental evolutionary graph theory [PDF]

open access: yesJournal of Theoretical Biology, 2014
Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have received relatively less attention.
Maciejewski, Wes, Puleo, Gregory J.
openaire   +4 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Genus Distribution for a Graph [PDF]

open access: yes, 2009
In this paper we develop the technique of a distribution decomposition for a graph. A formula is given to determine genus distribution of a cubic graph.
Liangxia, Wan   +2 more
core   +1 more source

Opportunities analysis the solution of the problems of the graph theory with computer mathematics systems

open access: yesLietuvos Matematikos Rinkinys, 2010
In this paper we analyze solutions of the problems of the graph theory with computer mathematics systems MAPLE and MATHEMATICA with purpose to reveal the opportunity of the syntax of the main commands, theirs similarities and differences.
Sigita Turskienė   +1 more
doaj   +1 more source

Geometric Graph Theory [PDF]

open access: yes, 1999
Note: Professor Pach's number: [172]; 2nd edition Reference DCG-CHAPTER-2008-027 Record created on 2008-11-18, modified on 2017-05 ...
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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