Results 111 to 120 of about 1,841,497 (380)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Graph theory based analysis of power system stability [PDF]

open access: yes, 2017
Graph theory based analysis of power system ...
Hill, DJ
core  

行星轮系的图论模型及其应用

open access: yesJixie chuandong, 2008
Through analysis of the graph theory model,the conditions that the EGTs’ graph theory model must be met is summarized.On the basis of graph theory model presented in literature[1],a concept of module entity and basic loop in graph theory model is ...
史晓影, 陈良钰, 薛隆泉
doaj  

Time-dependence of graph theory metrics in functional connectivity analysis [PDF]

open access: yesNeuroImage, 2016
Brain graphs provide a useful way to computationally model the network structure of the connectome, and this has led to increasing interest in the use of graph theory to quantitate and investigate the topological characteristics of the healthy brain and brain disorders on the network level.
Sharon Chiang   +6 more
openaire   +8 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Graph Theory Methods in Analysis of Model Structures [PDF]

open access: yes, 1978
The present paper consists of an introduction, in two parts and an appendix. The Introduction is devoted to the definition of the problem and describes, as a whole, the methods used.
Muchnik, I., Borodkin, L., Aven, P.O.
core  

Call Graph Soundness in Android Static Analysis [PDF]

open access: yes
peer reviewedStatic analysis is sound in theory, but an implementation may unsoundly fail to analyze all of a program's code. Any such omission is a serious threat to the validity of the tool's output.
BISSYANDE, Tegawendé François d Assise   +4 more
core   +1 more source

Graph Theory for Modeling and Analysis of the Human Lymphatic System

open access: yesMathematics, 2020
The human lymphatic system (HLS) is a complex network of lymphatic organs linked through the lymphatic vessels. We present a graph theory-based approach to model and analyze the human lymphatic network.
R. Savinkov   +5 more
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Graph Pattern Matching: From Intractable to Polynomial Time [PDF]

open access: yes, 2010
Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong   +5 more
core  

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