Results 121 to 130 of about 1,841,497 (380)

Graph theory [PDF]

open access: yes, 2016
International audienceOriginally a branch of mathematics designed to formalize the topological properties of networks, graph theory has evolved dramatically in the last two decades through interdisciplinary research encompassing both social and natural ...
Ducruet, César, César Ducruet
core   +1 more source

Altered EEG Brain Networks in Patients with Acute Peripheral Herpes Zoster

open access: yesJournal of Pain Research, 2021
Yan Zhou,1– 3 Zhenqin Liu,4 Yuanmei Sun,5 Hao Zhang,1,3 Jianghai Ruan1,3 1Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People’s Republic of China; 2Department of Neurology, Jianyang People’s Hospital ...
Zhou Y, Liu Z, Sun Y, Zhang H, Ruan J
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Theoretical Model for Accident Prevention Based on Root Cause Analysis With Graph Theory

open access: yesSafety and Health at Work, 2020
Introduction Despite huge investments in new technology and transportation infrastructure, terrible accidents still remain a reality of traffic. Methods Severe traffic accidents were analyzed from four prevailing modes of today's transportations: sea ...
Gregor Molan, Marija Molan
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Graph Drawing Techniques for Geographic Visualization [PDF]

open access: yes, 2004
Geovisualizers often need to represent data that consists of items related together. Such data sets can be abstracted to a mathematical structure, the graph.
Rodgers, Peter
core  

Regularity in Vague Intersection Graphs and Vague Line Graphs

open access: yesAbstract and Applied Analysis, 2014
Fuzzy graph theory is commonly used in computer science applications, particularly in database theory, data mining, neural networks, expert systems, cluster analysis, control theory, and image capturing.
Muhammad Akram   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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