Results 91 to 100 of about 278,990 (215)

Semi-Supervised Learning for Multi-View Data Classification and Visualization

open access: yesInformation
Data visualization has several advantages, such as representing vast amounts of data and visually demonstrating patterns within it. Manifold learning methods help us estimate lower-dimensional representations of data, thereby enabling more effective ...
Najmeh Ziraki   +2 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

On Kamada-Kawai graph layout with graph neural networks

open access: yesРадіоелектронні і комп'ютерні системи
Traditional force-directed layout algorithms, such as the Kamada-Kawai (KK) method, are widely used for graph visualization due to their ability to produce aesthetically pleasing layouts.
Olena Linnyk   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

The Analysis of Complex Networks with Dynamic Graph Visualization

open access: yesМоделирование и анализ информационных систем, 2010
The work describes a technique for dynamic graph visualization that helps us to analyze complex networks. Our method builds layouts for a sequence of graphs, while preserving the mental map. We show how to modify force-directed algorithms for the dynamic
S. N. Pupyrev, A. V. Tikhonov
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Juniper: A Tree+ Table Approach to Multivariate Graph Visualization. [PDF]

open access: yesIEEE Trans Vis Comput Graph, 2018
Nobre C, Streit M, Lex A.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

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