Results 111 to 120 of about 1,047,942 (207)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Software system for simulation of study of queuing system with heterogeneous servers and independent queues

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013
Software package for simulation of study and automated visualization of the state orgraph of queuing system with heterogeneous servers and independent limited queues is described. The base of the algorithm is the method of description of such queues with
Andrey P Kotenko, Maksim B Bukarenko
doaj  

Graph visualization using force algorithms [PDF]

, 2016
This article describes theory and realization of force-based graph visualization. There is an overview of aesthetic criteria of visualization. Article contains examples of visualization using force-based algorithms and describes the need to use different
Демешко, М. В., Дёмин, Антон Юрьевич   +1 more
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Land Use Thematic Maps Recommendation Based on Pan-Map Visualization Dimension Theory

Land
In the era of information and communication technology (ICT), the advancement of science and technology has led to a trend of diversification in map representation.
Yebin Chen, Zhicheng Shi, Yaxing Li, Dezhi Han, Minmin Li, Zhigang Zhao   +5 more
doaj   +1 more source

SoundBar: exploiting multiple views in multimodal graph browsing

, 2006
In this paper we discuss why access to mathematical graphs is problematic for visually impaired people. By a review of graph understanding theory and interviews with visually impaired users, we explain why current non-visual representations are unlikely ...
McGookin, D.K., Brewster, S.A., Stephen A. Brewster, David K. McGookin   +3 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

GraphXML - An XML-Based Graph Description Format

, 2001
GraphXML is a graph description language in XML that can be used as an interchange format for graph drawing and visualization packages. The generality and rich features of XML make it possible to define an interchange format that not only supports the ...
Herman, Ivan, Marshall, M. Scott, Ivan Herman, M. Scott Marshall   +3 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source