Results 41 to 50 of about 267,239 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Graph Drawing Techniques for Geographic Visualization [PDF]

open access: yes, 2004
Geovisualizers often need to represent data that consists of items related together. Such data sets can be abstracted to a mathematical structure, the graph.
Rodgers, Peter
core  

Spring Embedder Preprocessing for WWW Visualization [PDF]

open access: yes, 2002
We present a preprocessor for the spring embedder graph drawing method and show its use in speeding up the automatic layout of three-dimensional visualizations of WWW sites.
Mutton, P., Rodgers, P.
core   +1 more source

An Information-Theoretic Framework for Evaluating Edge Bundling Visualization

open access: yesEntropy, 2018
Edge bundling is a promising graph visualization approach to simplifying the visual result of a graph drawing. Plenty of edge bundling methods have been developed to generate diverse graph layouts.
Jieting Wu   +3 more
doaj   +1 more source

Navigation and Interaction in Graph Visualizations

open access: yesRevista de Informática Teórica e Aplicada, 2008
Graphs are widely utilized in many fields and several applications require their visualization. Graph visualization is based on techniques for graph drawing, interaction and navigation in such a way that helps the user in finding and manipulating information efficiently.
Spritzer, Andre Suslik   +1 more
openaire   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

KG4Vis: A knowledge graph-based approach for visualization recommendation

open access: yes, 2022
Visualization recommendation or automatic visualization generation can significantly lower the barriers for general users to rapidly create effective data visualizations, especially for those users without a background in data visualizations.
ZHANG, Songheng   +5 more
core   +1 more source

Indexing Structures for the Efficient Multi-Resolution Visualization of Big Graphs

open access: yesIEEE Access, 2023
Nowadays there is a great interest in the visualization of property graphs to make their navigation, inspection, and visual analysis easier. However, property graphs can be quite large and their rendering on web browsers can lead to a dark cloud of ...
Marco Mesiti   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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