Results 111 to 120 of about 267,239 (309)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

3DScape: three dimensional visualization plug-in for Cytoscape

open access: yes, 2011
3DScape is the first plug-in which enables three- dimensional network visualization in Cytoscape. The extra dimension is useful in accommodating, visualizing, and distinguishing larger networks with multiple crossing connections. ...
Qi Wang
core   +1 more source

Graph Visualization API Library for Application Builders

open access: yes, 2002
Founded in 1991, Tom Sawyer Software produces quality graph-based architectures for application developers. These technologies include graph management, graph layout, graph diagramming, and graph visualization technologies.
Gabe Grigorescu   +9 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Using adjacency matrices to lay out larger small-world networks

open access: yes, 2016
Many networks exhibit small-world properties. The structure of a small-world network is characterized by short average path lengths and high clustering coefficients.
Vickers, Paul, Gibson, Helen
core   +1 more source

The State-of-the-Art of Set Visualization [PDF]

open access: yes, 2016
Sets comprise a generic data model that has been used in a variety of data analysis problems. Such problems involve analysing and visualizing set relations between multiple sets defined over the same collection of elements. However, visualizing sets is a
Alsallakh, Bilal   +11 more
core   +1 more source

Construct a Knowledge Graph for China Coronavirus (COVID-19) Patient Information Tracking

open access: yesRisk Management and Healthcare Policy, 2021
Jiajing Wu1,2 1School of Information Science and Engineering, Ocean University of China, Qingdao, 265100,People’s Republic of China; 2School of Mathematics and Computer Science, Chifeng University, Chifeng City, 024000, Inner Mongolia, People’s Republic ...
Wu J
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Interaction on graphs using non-conventional devices

open access: yesJournal of Computer Science and Technology, 2007
Interactions become essential in Visualization because they enable users to adapt the visual representation to their own needs allowing them to explore the underlying information space.
Sebastián Escarza   +2 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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