Results 41 to 50 of about 258,723 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Software for Graph Analysis and Visualization

open access: yesМоделирование и анализ информационных систем, 2014
This paper describes the software for graph storage, analysis and visualization. The article presents a comparative analysis of existing software for analysis and visualization of graphs, describes the overall architecture of application and basic ...
M. I. Kolomeychenko   +3 more
doaj   +1 more source

Pan-genome de Bruijn graph using the bidirectional FM-index

open access: yesBMC Bioinformatics, 2023
Background Pan-genome graphs are gaining importance in the field of bioinformatics as data structures to represent and jointly analyze multiple genomes. Compacted de Bruijn graphs are inherently suited for this purpose, as their graph topology naturally ...
Lore Depuydt   +3 more
doaj   +1 more source

Indexing Structures for the Efficient Multi-Resolution Visualization of Big Graphs

open access: yesIEEE Access, 2023
Nowadays there is a great interest in the visualization of property graphs to make their navigation, inspection, and visual analysis easier. However, property graphs can be quite large and their rendering on web browsers can lead to a dark cloud of ...
Marco Mesiti   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Visualization of the Graph of the Dependence of Terms in the Training Material

open access: yesСовременные информационные технологии и IT-образование, 2020
The article deals with the problem of creating training courses. When constructing a course, the teacher periodically needs tools for visualizing the structure of the future course.
Andrey Filipov
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Parallel graph layout algorithm for large-scale graph data

open access: yes大数据, 2016
Graph models are modeling tools which are widely used.Data visualization techniques have been widely used as intuitive data analysis tools.Graph layout algorithm is the most critical technique of graph visualization,while there are no effective parallel ...
Zhiyuan CHENG, Yubin BAO, Fangling LENG
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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