Results 61 to 70 of about 47,436 (306)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

DIE GRAPHIC NOVEL IM FREMDSPRACHENUNTERRICHT

open access: yesStudia Universitatis Babeş-Bolyai. Philologia, 2017
Graphic Novel in Foreign Language Class. Working with graphic novels in a foreign language class increases the motivation of learners towards the language.
Jeannine FEIX
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Graphic Representation and Drawing

open access: yesProceedings, 2017
Graphic representation is one of the main systems of signs designed by man with the aim of preserving, understanding, and communicating information deemed essential.
Maurizio Marco Bocconcino
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Digital Code as an Object Graphic Design for Dissemination and Promotion of Brand

open access: yesMeno Istorija ir Kritika, 2023
The article reveals the features of the graphic language of coded information by identifying, systematizing, and combining QR-codes and AR-codes at the present stage of graphic design development.
Vorobchuk Maria, Pashkevych Kalina
doaj   +1 more source

Describing verbal graphic language

open access: yes, 1982
This paper describes part of continuing research which is concerned with description of visual organization of verbal graphic language. There are no recognized descriptive techniques for studying spatial and graphic articulation of VGL, and the method ...
Sue Walker
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Phenomenon of Graphic Substitution in Internet Discourse

open access: yesИзвестия Южного федерального университета: Филологические науки, 2019
The article is devoted to the study of graphic substitutes in the language of Internet communication. The authors identified and described the main ways of graphical transformation of language phenomena at the level of supragraphics, syngraphics and ...
Elena A. Kalinovskaya, Anna S. Kobysheva
doaj   +1 more source

Graphic codes, language, and the computational niche

open access: yesBehavioral and Brain Sciences, 2023
Abstract Human language looms large in the emergence and evolution of graphic codes. Here, I argue that language not only acts as a strong constraint on graphic codes, but it is also a precondition for their emergence and their evolution as computational devices.
openaire   +2 more sources

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