Results 1 to 10 of about 66,171 (303)

Grey Skin, Grey Water: Iterations of Bhartrhari’s Sphota in Amruta Patil’s Kari

open access: yesILN Journal: Indian Literary Narratives
This article examines Bhartrhari’s concept of sphota as a critical framework for interpreting the intermedial dynamics of text and image in contemporary graphic narratives, with specific reference to Amruta Patil’s Kari.
Uma Madhu, Prof. Amith Kumar P.V
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A Graphic Novel: John McCloskey and Breandán Ó Conaire on the Making of An Béal Bocht

open access: yesThe Parish Review, 2013
In 2012, Cló Mhaigh Eo published a graphic novel version of Myles na gCopaleen’s satirical work An Béal Bocht. Adapted from the original by Colmán Ó Raghallaigh and edited by Breandán Ó Conaire, author of Myles na Gaeilge (1986), the book features the ...
Jennika Baines
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Umberto Eco’s The Mysterious Flame of Queen Loana: A conduit for culture, consciousness and cognition

open access: yesInkanyiso, 2010
Eco’s novel describes the popular culture of the Italian fascist period, by deconstructing signs, symbols and signals from a particular period in the lives of both the author and his protagonist.
Marie Spruyt
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Os sons das palavras: possibilidades e limites da novela gráfica

open access: yesEstudos de Literatura Brasileira Contemporânea, 2011
The graphic novel today aims to a literary status, but its attributes at the same time favor such possibility and frustate it. In this analysis, I demonstrate how time control by the artists is at the center of this process. Halting the reader, distract-
Elvira Vigna
doaj  

MODULATION AS A MULTIMODAL TRANSLATION STRATEGY OF GRAPHIC NOVEL PERSEPOLIS BY M. SATRAPI [PDF]

open access: yesAlfred Nobel University Journal of Philology
The article presents a specific perspective on modulation as a universal strategy for translating multimodal graphic novel, while exploring the interplay between visual and verbal elements in meaning construction.
Anna V. Khodorenko
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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