Results 31 to 40 of about 414,825 (300)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Novel Graphical Evaluation of Agreement [PDF]

open access: yesBMC Medical Research Methodology, 2020
Abstract Background: The Bland-Altman plot with limit of agreement has been widely used as a visual tool for assessing test-retest reliability or reproducibility between two measurements. We have observed, however, that in certain circumstances the limit of agreement approach may mislead practitioners. Particularly, if the acceptable difference
Jongphil Kim, Ji-Hyun Lee
openaire   +4 more sources

MAKING MEANING USING SYSTEMIC FUNCTIONAL LINGUISTICS AND VISUAL GRAMMAR ANALYSIS: COMPARISON OF SOURCE TEXT AND TARGET TEXT REFLECTED IN THE MAIN CHARACTER OF GRAPHIC NOVEL V FOR VENDETTA [PDF]

open access: yes, 2017
This research presents a project designed to investigate a systemic way of analyzing metafunctions’ shifts between source texts and target texts using systemic functional linguistic (SFL) collaborated with visual grammar (VS; systemic functional ...
Nababan, Nababan   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Autori egiziani degli anni Duemila. Blogosfera, graphic e postmoderno: nuovi linguaggi nel panorama letterario arabo

open access: yesKervan. International Journal of Afro-Asiatic Studies, 2016
The first decade of the new millennium represents a crucial change for Egyptian civil society and its means of expression. This paper presents a brief overview of some new narrative forms developed in those years that were a prelude to the movement of ...
Lucia Avallone
doaj   +1 more source

Hugo Pratt’s and Milo Manara’s Indian Summer: An Italian “Source” for The Scarlet Letter [PDF]

open access: yes, 2017
This paper examines the allusions of Milo Manara’s and Hugo Pratt’s graphic novel, Tutto ricominciò con un’estate indiana (Indian Summer), to Hawthorne’s novel The Scarlett Letter in a variety of ways.
Mariani, Giorgio
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Qu’en est-il du roman graphique portugais ?

open access: yesCahiers d’Études Romanes, 2018
The graphic novel, with a strong syncretism with respect to genre, has become nowadays a form of textuality resulting from more or less complex relationships between iconic signs and verbal signs, with iteratively revisited questions about its belonging ...
Isabel Margarida Duarte   +1 more
doaj   +1 more source

Putting it to the Comic Book Fans: Is Auckland Libraries’ Comic Book/Graphic Novel and Manga Collection Meeting Customer Expectations?

open access: yes, 2012
This study examines whether Auckland Libraries’ comic book/graphic novel and manga collection is meeting customer expectations and ascertains possible improvements that could be made.
Priest, Michael James
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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