Results 51 to 60 of about 414,825 (300)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Re-telling, re-evaluating and re-constructing [PDF]
, 2013 'Graphic History: Essays on Graphic Novels and/as History '(2012) is a collection of 14 unique essays, edited by scholar Richard Iadonisi, that explores a variety of complex issues within the graphic novel medium as a means of historical narration.
Tolja, Gorana
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
ILN Journal: Indian Literary NarrativesThis study investigates the impact of graphic novels The Bad Doctor and The Lady Doctor by Ian Williams on reader engagement, empathy, and emotional response. Utilizing a structured questionnaire distributed among a sample of English literature students,
Garret Raja, Nisha Anil Salunkhe
doaj +1 more source
La Bogotá distópica: los cómics sobre una ciudad en caos
Co-herencia: Revista de Humanidades, 2019 This paper explores the narrative and visual resourcesused in Colombian comics, from 1992 to the presentday, in order to describe dystopian representations of Bogotá city.
Sergio Roncallo-Dow +2 more
doaj +1 more source
Rozprawy Społeczne, 2020 This article presents the results of a critical translational analysis of the translation of the German graphic novel “Kinderland” by Grzegorz Janusz into Polish.
Katarzyna Barbara Tymoszuk
doaj +1 more source
Graphic novel: The superhero of research dissemination? [PDF]
, 2013 When the main output from a research project is essentially a report and a few lofty journal articles what does this mean for impact? Well, as researchers, we hope it means quite a lot. We hope that key policy makers and practitioners will read our work,
Brown, Philip
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source