Results 41 to 50 of about 4,921,772 (293)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Adventures of the Graphic Novel in Turkey
, 2019 This chapter describes how the graphic novel was initially translated, adapted, and appropriated in the Turkish cultural and literary polysystem from the West in the early years of the Turkish Republic (1923). The transfer enabled the graphic novel to be
Aksoy,N.B.
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
On the trails of the graphic novel
, 2020 Review the book Graphic novel: conceitos básicos, by Nobu Chinen.Faz a resenha do livro Graphic novel: conceitos básicos, de Nobu ...
Vergueiro, Waldomiro
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Zeitschrift für Interkulturellen Fremdsprachenunterricht, 2019 Der vorliegende Beitrag untersucht die künstlerisch inszenierte symbiotische Verschränkung von Bild und Text in der Graphic Novel Der nasse Fisch. Die Auseinandersetzung mit der Graphic Novel erfolgt auf Seiten der LeserInnen auf eine andere Art und ...
Benjamin Nickl, Tristan Lay
doaj +1 more source
La Bogotá distópica: los cómics sobre una ciudad en caos
Co-herencia: Revista de Humanidades, 2019 This paper explores the narrative and visual resourcesused in Colombian comics, from 1992 to the presentday, in order to describe dystopian representations of Bogotá city.
Sergio Roncallo-Dow +2 more
doaj +1 more source