Results 71 to 80 of about 5,227 (304)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Graphic Novels and Comics in Undergraduate and Graduate Medical Students Education: A Scoping Review. [PDF]
Eur J Investig Health Psychol Educ, 2023 Consorti F +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Book Review: Manga in Libraries: A Guide for Teen Librarians
Journal of Anime and Manga StudiesManga, comics or graphic novels originating from Japan, are popular both inside and outside of Japan. Sales of manga have quadrupled since 2020. In 2023, almost 49% of graphic novels sold were manga.
Sara Lowe
doaj +1 more source
Use of A Comic Book to Assist Student Learning of Dimensions of Patient-Centered Care
INNOVATIONS in Pharmacy, 2016 Objective: To evaluate the use of comic books as a supplemental reading to assist student learning of the dimensions of patient-centered care. The Innovation: A comic book titled Mom’s Cancer was used as a supplemental reading in a course that introduced
Jagannath Muzumdar
doaj +1 more source
Reducing the anxiety of patients undergoing an oral biopsy by means of graphic novels: an open-label randomized clinical trial. [PDF]
Med Oral Patol Oral Cir Bucal, 2023 Bazzano M +3 more
europepmc +1 more source
Researching Graphic Novels and Their Teenage Readers [PDF]
, 2007 Graphic novels are becoming more prevalent and popular among teenagers and are thus being collected by public and school libraries. This situation contributed to the doctoral researcher's desire to investigate graphic novel collections in public ...
Snowball, Clare
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 2011 Graphic texts, or graphic novels, have spent many years on shelves with comic books about superheroes and adventurers. They officially gained notoriety in 1992 with Art Spiegelman’s Maus, and at this time, critics and scholars began to take notice ...
Phelps, Valarie L.
core