Results 101 to 110 of about 7,119,691 (324)

On the evolution by fractional mean curvature

, 2019
In this paper we study smooth solutions to a fractional mean curvature flow equation. We establish a comparison principle and consequences such as uniqueness and finite extinction time for compact solutions.
Sáez, Mariel, Valdinoci, Enrico
core   +1 more source

Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests

Biometrical journal. Biometrische Zeitschrift, 2011
The confirmatory analysis of pre‐specified multiple hypotheses has become common in pivotal clinical trials. In the recent past multiple test procedures have been developed that reflect the relative importance of different study objectives, such as fixed
F. Bretz, M. Posch, E. Glimm, Florian Klinglmueller, W. Maurer, Kornelius Rohmeyer   +5 more
semanticscholar   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Finite Element Assisted Study of Magnetic Configurations of Flat Pickups for Inductively Coupled Power Transfer Systems

, 2006
This publication describes the findings from a finite-element assisted study of an Inductively Coupled Power Transfer (ICPT) system with flat pickups. Results from the analysis of pickup elements are presented in a graphical form allowing comparison with
Kacprzak, D., Sykulski, J.K.
core  

CalcHEP 3.4 for collider physics within and beyond the Standard Model

, 2012
We present version 3.4 of the CalcHEP software package which is designed for effective evaluation and simulation of high energy physics collider processes at parton level.
Alexander Belyaev, Alexander Pukhov, Allanach, Allanach, Alwall, Alwall, Alwall, Baikov, Barbieri, Belanger, Belanger, Belanger, Belanger, Belanger, Belanger, Belanger, Belanger, Belov, Belyaev, Belyaev, Bjorken, Boos, Cafarella, Chetyrkin, Christensen, de Aquino, Degrande, Djouadi, Djouadi, Ellwanger, Gleisberg, Gleisberg, Hahn, Hahn, Kanaki, Kawabata, Kublbeck, Kublbeck, Lee, Lepage, Lopez Honorez, Maltoni, Muhlleitner, Neil D. Christensen, Papadopoulos, Porod, Press, Pukhov, Semenov, Semenov, Sjostrand, Skands, Spira, Tanaka, Yuasa   +54 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The dynamics of a new chaotic system through the Caputo–Fabrizio and Atanagan–Baleanu fractional operators

Advances in Mechanical Engineering, 2019
The aim of this article is to analyze the dynamics of the new chaotic system in the sense of two fractional operators, that is, the Caputo–Fabrizio and the Atangana–Baleanu derivatives.
Muhammad Altaf Khan
doaj   +1 more source

The polarimeter and the multispectral radiometer as remote probes of aerosols [PDF]

Attempts made to establish the viability of the polarimeter as a ground based remote probe of atmospheric aerosols under varying meteorological conditions are reported.
Kuriyan, J. G.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source